Summary
International Symposium on Nonlinear Theory and Its Applications
2015
Session Number:B3L-F
Session:
Number:B3L-F-2
Periodic Fluctuation Observed in an Ensemble Firing of Neurons in a Cortical Network Model of Correlated Bidirectional Connections
Hisashi Kada, Jun-Nosuke Teramae, Isao T. Tokuda,
pp.636-639
Publication Date:2015/12/1
Online ISSN:2188-5079
Summary:
In cortical networks, it has been known that neurons generate self-sustained low-frequency firings in the absence of sensory stimuli. The so-called ``spontaneous activity" typically gives rise to irregular and asynchronous firing among cortical neurons. Despite numerous theoretical attempts, the mechanism underlying the spontaneous activity remained unclear. A breakthrough has been recently made by Teramae et al. who proposed a neuronal network model, in which EPSPs (Excitatory postsynaptic potentials) obey a lognormal distribution. The model implied that the lognormal distribution of EPSPs in cortical networks was the key to sustain low-frequency firing of the neurons. Whereas their model mainly focused on the lognormal distribution, correlation of the EPSPs observed between bidirectionally coupled neurons has been disre garded. In our previous study, we added correlated EPSPs to the lognormal network and showed that the correlated EPSPs generated synchronized firing among the neurons. Extremely high firing frequencies were also observed in a group of neurons. The aim of this paper is to study further details of the neuronal dynamics in a network of correlated EPSPs. We show that periodic fluctuations exist in shortterm population firing of the neurons. Such periodic fluctuations seem to arise from periodic spikings of neurons with high firing frequencies.