Summary
International Symposium on Nonlinear Theory and Its Applications
2016
Session Number:A2L-B
Session:
Number:A2L-B-2
Bifurcation Analysis for Early Afterdepolarization in Shannon Model
Ai Takahashi, Hiroyuki Kitajima, Toru Yazawa,
pp.-
Publication Date:2016/11/27
Online ISSN:2188-5079
Summary:
The membrane potential of the ventricular myocyte is regulated through inward and outward ionic currents. When these electrical activities are disturbed, arrhythmia occurs. In particular, the QT prolongation is considered to be a sign of sudden cardiac death. In this study we investigate the relationship between the conductivities of ionic currents and the occurrence of such arrhythmias. We obtain that the QT prolongation relates to the conductivities of the sodium-calcium exchange current and the Ltype calcium current.