Summary
International Symposium on Nonlinear Theory and Its Applications
2015
Session Number:B2L-C
Session:
Number:B2L-C-5
Computational Simulation: Local Inhibitory Synapses Activate Cortical Regions Around the Lesion
Hiroyuki Kitano, Katsuhiko Hata, Yuta Kakimoto, Tomokazu Urakawa, Osamu Araki,
pp.459-462
Publication Date:2015/12/1
Online ISSN:2188-5079
Summary:
It has been known that the neural activity around the cortical lesion tends to arise. We simulated this phenomenon using a neural network model composed of excitatory and inhibitory neurons with strong-sparse and weak-dense connections, whose inhibitory ones are projected on neighboring neurons. Increased average membrane potentials in perilesional neurons were observed after damaging the injury. It is suggested that the activated neurons have lost more inhibitory projections from the neighboring injured region than excitatory ones.