Summary

2023

Session Number:C4L-1

Session:

Number:C4L-14

Engineering Approaches to Control Biological Responses - ‘Fabricating Neural Circuitry’

Merryweather Daniel,  Earl Dan,  Marcos Luis,  Jenkins David,  Parri Rhein,  Hill Eric,  Roach Paul,  

pp.599-600

Publication Date:2023-09-21

Online ISSN:2188-5079

DOI:10.34385/proc.76.C4L-14

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Summary:
Using microfabrication techniques we demonstrate the production of a bespoke multi-population living neuronal network. Using bespoke microchannel internal geometry, we show directed cell mobility and guided connectivity through use of micro-channels in polydimethylsiloxane (PDMS) devices. These networks are demonstrated using both a SY-SY5Y cell line and larger cell clusters.