Summary
International Symposium on Nonlinear Theory and Its Applications
2015
Session Number:A2L-B
Session:
Number:A2L-B-3
Influence of Ionic Currents on a Simple Model for Pancreatic ﾎｲCells
Hiroyasu Ando, Kantaro Fujiwara,
pp.26-29
Publication Date:2015/12/1
Online ISSN:2188-5079
Summary:
Pancreatic ﾎｲcells exhibit bursting electrical activity, which is correlated with insulin secretion. It has been reported that several ionic channels may contribute to their characteristic electrical activity, but the mechanism of electrical activity in pancreatic ﾎｲcells is still unclear. In this study, we investigate the influence of ionic currents on a simple model for pancreatic ﾎｲcells. Our findings from mathematical modeling imply that the difference of activity patterns in ﾎｲcells can be explained by the difference of ionic currents which produce bursting activity.