Summary
International Symposium on Nonlinear Theory and Its Applications
2016
Session Number:A4L-F
Session:
Number:A4L-F-5
Alternans Generation in the Crustacean Heart Model: a Simulation - Electrophysiology Study
Toru Yazawa, Hiroyuki Kitajima,
pp.-
Publication Date:2016/11/27
Online ISSN:2188-5079
Summary:
Alternans-rhythm indicates an unhealthy state of the heart but this 2-beat rhythm is still required further studies. With gathering real-world data of alternans, we characterized its ill-condition using modified detrended fluctuation analysis (mDFA), and also determined ionic mechanisms for generating alternans using a numerical simulation. Alternans-electrocardiograms were recorded from various ``hearted'' animals including humans. We foud: (1) Alternans decreases the scaling exponents which can quantify the state of the circulatory system. (2) Simulation analysis reveals that mainly K+ and/or Na+ ionic mechanisms can explain how and why the heart system generate alternans.