Summary
2007 International Symposium on Nonlinear Theory and its Applications
2007
Session Number:19AM2-B
Session:
Number:19AM2-B-3
Significance of LTD Window in the Range of Positive Spike Timing of STDP Rule for Theta Phase Coding in a Network Having Background Noise
Jun Igarashi, Hatsuo Hayashi,
pp.425-428
Publication Date:2007/9/16
Online ISSN:2188-5079
DOI:10.34385/proc.41.19AM2-B-3
Summary:
The hippocampus and the entorhinal cortex generate theta rhythm that is an underlying mechanism for sequence learning. Background noise also exists in those areas. Since synapses have features of spike-timing dependent plasticity (STDP), it is possible that background noise causes enhancement of irrelevant synaptic connections that obscure memory encoding. In the present study, we tested the significance of the LTD window for robust sequence learning amid background noise, using our previous model of the entorhinal cortex layer II. Our results indicate that a LTD window in the range of positive spike timing works well, with the progress of the sequence learning, to suppress the enhancement of irrelevant connections between neurons; one of which receives regular and random pulse trains both, and each of the other cells receives only a random pulse train.