Presentation	2015-01-28 Double-Strand Break of Genomic DNA : Is Ultrasound safe enough? Kenichi Yoshikawa,
PDF Download Page	PDF download Page Link
Abstract(in Japanese)	(See Japanese page)
Abstract(in English)	It is well known that double-strand breaks of DNA induce mutagenic and carcinogenic processes in living cells. Unfortunately, through the currently available experimental methodologies it has been almost impossible to evaluate the double-strand breaks in a quantitative matter. We have recently been shown that single-molecule observation on giant DNA molecules provides reliable information on the degree of double-strand breaks. In the present paper, we will describe the difference of the mechanism of double-strand breaks in DNA induced by different damage sources, ultrasound, 7-ray and photo-excitation, by utilizing the methodology of single DNA observation in aqueous solution.
Keyword(in Japanese)	(See Japanese page)
Keyword(in English)	Double-Strand Break / Genomic DNA / DNA damage / Single Molecule Observation
Paper #	US2014-82,EA2014-61
Date of Issue

Conference Information
Committee	EA
Conference Date	2015/1/21(1days)
Place (in Japanese)	(See Japanese page)
Place (in English)
Topics (in Japanese)	(See Japanese page)
Topics (in English)
Chair
Vice Chair
Secretary
Assistant

Paper Information
Registration To	Engineering Acoustics (EA)
Language	JPN
Title (in Japanese)	(See Japanese page)
Sub Title (in Japanese)	(See Japanese page)
Title (in English)	Double-Strand Break of Genomic DNA : Is Ultrasound safe enough?
Sub Title (in English)
Keyword(1)	Double-Strand Break
Keyword(2)	Genomic DNA
Keyword(3)	DNA damage
Keyword(4)	Single Molecule Observation
1st Author's Name	Kenichi Yoshikawa
1st Author's Affiliation	Faculty of Life and Medical Sciences, Doshisha University()
Date	2015-01-28
Paper #	US2014-82,EA2014-61
Volume (vol)	vol.114
Number (no)	423
Page	pp.pp.-
#Pages	3
Date of Issue