Presentation 2014-07-11
Estimation of parylen-C diaphragm deformation induced by molecular adsorption on a Fabry-Perot interferometric biosensor
Yoshihiro MASUYA, Kazuhiro TAKAHASHI, Ryo OZAWA, Makoto ISHIDA, Kazuaki SAWADA,
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Abstract(in English) We have recently developed a surface stress sensor based on a MEMS Fabry-Perot interferometer integrated with a photodiode, which utilizes the nonlinear optical transmittance change in the Fabry-Perot interference to enhance the sensitivity of the surface stress. Parylene-C was used as a deformable membrane in the sensor because of negligible residual stress and low Young's modulus of 2.8 GPa, which provides a large deformation with respect to molecular adsorption. After immobilization of 2-pg anti-BSA on the Fabry-Perot sensor, we measured about 50nm deformation by optical surface profiler and reflection spectrum.
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Keyword(in English) MEMS Fabry-Perot interferometer / biosensor / label-free / surface-stress / protein
Paper # ED2014-52
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Committee ED
Conference Date 2014/7/3(1days)
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Language JPN
Title (in Japanese) (See Japanese page)
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Title (in English) Estimation of parylen-C diaphragm deformation induced by molecular adsorption on a Fabry-Perot interferometric biosensor
Sub Title (in English)
Keyword(1) MEMS Fabry-Perot interferometer
Keyword(2) biosensor
Keyword(3) label-free
Keyword(4) surface-stress
Keyword(5) protein
1st Author's Name Yoshihiro MASUYA
1st Author's Affiliation Toyohashi University of Technology()
2nd Author's Name Kazuhiro TAKAHASHI
2nd Author's Affiliation Toyohashi University of Technology
3rd Author's Name Ryo OZAWA
3rd Author's Affiliation Toyohashi University of Technology
4th Author's Name Makoto ISHIDA
4th Author's Affiliation Toyohashi University of Technology:EIIRIS, Toyohashi University of Technology
5th Author's Name Kazuaki SAWADA
5th Author's Affiliation Toyohashi University of Technology:EIIRIS, Toyohashi University of Technology
Date 2014-07-11
Paper # ED2014-52
Volume (vol) vol.114
Number (no) 133
Page pp.pp.-
#Pages 5
Date of Issue