| Presentation | 2014-03-17 Regulation of acetylcholine to excitatory postsynaptic potential and spike back-propagation in hippocampal CA1 dendrite Gaku KAIEDA, Masashi KONDO, Takeshi AIHARA, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Acetylcholine (ACh) acts as a "modulator" on the initiation of synaptic plasticity. The retrograde spikes called back-propagating action potentials (bAPs) is considered to play an important role in the initiation of synaptic plasticity. The purpose of this study was how acetylcholine influences the bAP along dendrites. To probe the spatio-temporal dynamics of bAP, we employed an optical imaging method with voltage-sensitive dye. As a result, the amplitude of bAP was suppressed by carbachol, acetylcholine receptor agonist.. Therefore, the synaptic plasticity along dendrites could be affected by means of the suppression of bAPs. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | back-propagating action potential / acetylcholine / EPSP(excitatory post-synaptic potential) / Optical imaging / voltage-sensitive dye |
| Paper # | MBE2013-115 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2014/3/10(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Regulation of acetylcholine to excitatory postsynaptic potential and spike back-propagation in hippocampal CA1 dendrite |
| Sub Title (in English) | |
| Keyword(1) | back-propagating action potential |
| Keyword(2) | acetylcholine |
| Keyword(3) | EPSP(excitatory post-synaptic potential) |
| Keyword(4) | Optical imaging |
| Keyword(5) | voltage-sensitive dye |
| 1st Author's Name | Gaku KAIEDA |
| 1st Author's Affiliation | Graduate School of Engineering Tamagawa University() |
| 2nd Author's Name | Masashi KONDO |
| 2nd Author's Affiliation | Graduate School of Brain Sciences Tamagawa University |
| 3rd Author's Name | Takeshi AIHARA |
| 3rd Author's Affiliation | Graduate School of Engineering Tamagawa University:Graduate School of Brain Sciences Tamagawa University |
| Date | 2014-03-17 |
| Paper # | MBE2013-115 |
| Volume (vol) | vol.113 |
| Number (no) | 499 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |