Presentation 2014-03-10
Jet lag induces desynchronization in the circadian clock
Hideyuki KATO, Hiroshi KORI,
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Abstract(in English) Circadian rhythm is disordered by jet lag. It is considered that the disorder derives from a collapse of circadian rhythm synchronization in suprachiasmatic nucleus (SCN), which is the master clock of the circadian rhythm. However, its mechanism is still unclear. In this study, we developed a mathematical model of the SCN that is composed of two populations of globally coupled phase oscillators. We will show that the model exhibits behaviors in a typical jet lag symptom as observed in experiments: an eight-hour-phase advance causes a terrible jet lag and it takes eight or nine days to recover from it.
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Keyword(in English) ircadian rhythm / synchronization / desynchronization / jet lag / phase oscillators / global coupling
Paper # NLP2013-169
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Committee NLP
Conference Date 2014/3/3(1days)
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Registration To Nonlinear Problems (NLP)
Language ENG
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Jet lag induces desynchronization in the circadian clock
Sub Title (in English)
Keyword(1) ircadian rhythm
Keyword(2) synchronization
Keyword(3) desynchronization
Keyword(4) jet lag
Keyword(5) phase oscillators
Keyword(6) global coupling
1st Author's Name Hideyuki KATO
1st Author's Affiliation Center for Simulation Sciences, Ochanomizu University()
2nd Author's Name Hiroshi KORI
2nd Author's Affiliation Center for Simulation Sciences, Ochanomizu University
Date 2014-03-10
Paper # NLP2013-169
Volume (vol) vol.113
Number (no) 486
Page pp.pp.-
#Pages 6
Date of Issue