Presentation	2014-01-23 Study of Magnetic Particle Imaging (MPI) using HTS-SQUID by Detection of Second Harmonics Tomoya OISHI, Hayaki MURATA, Zhang Yi, Yoshimi HATSUKADE, Saburo TANAKA,
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Abstract(in English)	We have developed a method to improve the detection sensitivity for the magnetization M of magnetic nanoparticles (MNP). The M response of MNP was systematically analyzed and experimentally proven. A high sensitive device, HTS-SQUID magnetometer was applied to the MPI. The M response of MNP to an applied magnetic field H(M-H characteristics) could be divided into a linear region and a saturation region, which are separated at a knee field H_k. When applying an excitation AC magnetic field (H_) and an additional DC bias field (H_), the second harmonic of M reaches the maximum at a knee point due to the nonlinearity of the M-H characteristics. The advantage of the use the second harmonic response is that the response can be taken for small H_. It is 7 times larger than a third harmonic. Then we could successfully demonstrate the 1D image of two separated bottle-shaped phantom filled with MNP using a lock-in amplifier.
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Keyword(in English)	SQUID / Magnetic Particle Imaging / MPI / Magnetic Nanoparticles / MNP / Imaging
Paper #	SCE2013-40
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Conference Information
Committee	SCE
Conference Date	2014/1/16(1days)
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Paper Information
Registration To	Superconductive Electronics (SCE)
Language	JPN
Title (in Japanese)	(See Japanese page)
Sub Title (in Japanese)	(See Japanese page)
Title (in English)	Study of Magnetic Particle Imaging (MPI) using HTS-SQUID by Detection of Second Harmonics
Sub Title (in English)
Keyword(1)	SQUID
Keyword(2)	Magnetic Particle Imaging
Keyword(3)	MPI
Keyword(4)	Magnetic Nanoparticles
Keyword(5)	MNP
Keyword(6)	Imaging
1st Author's Name	Tomoya OISHI
1st Author's Affiliation	Toyohashi University of Technology()
2nd Author's Name	Hayaki MURATA
2nd Author's Affiliation	Toyohashi University of Technology
3rd Author's Name	Zhang Yi
3rd Author's Affiliation	Peter Gruenberg Institute, Forschungszentrum Juelich
4th Author's Name	Yoshimi HATSUKADE
4th Author's Affiliation	Toyohashi University of Technology
5th Author's Name	Saburo TANAKA
5th Author's Affiliation	Toyohashi University of Technology
Date	2014-01-23
Paper #	SCE2013-40
Volume (vol)	vol.113
Number (no)	401
Page	pp.pp.-
#Pages	6
Date of Issue