| Presentation | 2013-07-18 Quantitative Analysis of Amyloid Deposits in PET/CT Images Kei Sasaki, Norihide Maikusa, Tetsuya Yuasa, Etsuko Imabayashi, Hiroshi Matsuda, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | For early diagnosis of Alzheimer's disease (AD), it is effective to quantitatively evaluate deposits of amyloid into gray matter, which can be estimated from an Amyloid PET (Positron Emission Tomography) image. However, the deposit quantity in gray matter tends to be underestimated, which is caused by partial volume effect (PVE) due to the lower spatial resolution of PET. This study proposes a method to correct the PVE of a PET image using an X-ray CT image, where they are simultaneously acquired by PET/CT, and to restore the quantitative property in evaluating deposits of amyloid. We show the effectiveness by comparing the result based on an X-ray CT image with that based on an MRI image, obtained from a healthy volunteer. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | PET/CT / Alzheimer's disease / partial volume effect / amyloid imaging |
| Paper # | MI2013-28 |
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| Conference Information | |
| Committee | MI |
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| Conference Date | 2013/7/11(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Medical Imaging (MI) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Quantitative Analysis of Amyloid Deposits in PET/CT Images |
| Sub Title (in English) | |
| Keyword(1) | PET/CT |
| Keyword(2) | Alzheimer's disease |
| Keyword(3) | partial volume effect |
| Keyword(4) | amyloid imaging |
| 1st Author's Name | Kei Sasaki |
| 1st Author's Affiliation | Graduate School of Science and Engineering, Yamagata University:National Center of Neurology and Psychiatry() |
| 2nd Author's Name | Norihide Maikusa |
| 2nd Author's Affiliation | National Center of Neurology and Psychiatry |
| 3rd Author's Name | Tetsuya Yuasa |
| 3rd Author's Affiliation | Graduate School of Science and Engineering, Yamagata University |
| 4th Author's Name | Etsuko Imabayashi |
| 4th Author's Affiliation | Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology |
| 5th Author's Name | Hiroshi Matsuda |
| 5th Author's Affiliation | National Center of Neurology and Psychiatry |
| Date | 2013-07-18 |
| Paper # | MI2013-28 |
| Volume (vol) | vol.113 |
| Number (no) | 146 |
| Page | pp.pp.- |
| #Pages | 5 |
| Date of Issue | |