Presentation | 2013/6/20 Non-coding RNA analysis for gene expression regulation using bioinformatics tools CHISATO HAYASHI, YEONDAE KWON, SATORU MIYAZAKI, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | Advances in genome analysis have revealed that a genomic DNA contains gene coding regions other than protein coding sequences and transcription-regulating regions. Among these regions, there exist RNA coding regions involved in transcription regulation as a primary function, RNAs transcribed from these regions are referred to as non-coding RNAs (ncRNAs). ncRNAs are known to affect regulation of transcription, but many functions are still unknown. On the other hand, since some ncRNAs specifically express in a particular disease, they may have potential for being used as drug targets. Also, while most of ncRNAs currently observed locate on intergenic regions of protein coding genes, some ncRNAs locate on intronic regions of protein coding genes. The aim of this work is to predict ncRNAs as drug targets regulating disease-associated genes based on positional relationship between protein genes and ncRNAs on a genome. In this paper, we compare ncRNAs located on intronic regions across species. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | non-coding RNA / gene expression / intron / database |
Paper # | Vol.2013-BIO-34 No.2 |
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Committee | NC |
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Conference Date | 2013/6/20(1days) |
Place (in Japanese) | (See Japanese page) |
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Registration To | Neurocomputing (NC) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Non-coding RNA analysis for gene expression regulation using bioinformatics tools |
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Keyword(1) | non-coding RNA |
Keyword(2) | gene expression |
Keyword(3) | intron |
Keyword(4) | database |
1st Author's Name | CHISATO HAYASHI |
1st Author's Affiliation | Graduate School of Pharmaceutical Sciences, Tokyo University of Science() |
2nd Author's Name | YEONDAE KWON |
2nd Author's Affiliation | Department of Medical and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science |
3rd Author's Name | SATORU MIYAZAKI |
3rd Author's Affiliation | Department of Medical and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science |
Date | 2013/6/20 |
Paper # | Vol.2013-BIO-34 No.2 |
Volume (vol) | vol.113 |
Number (no) | 111 |
Page | pp.pp.- |
#Pages | 6 |
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