Presentation 2013-04-26
Biocompatible Comb-type Copolymer to form Self-assembled Monolayer
Hidenori OTSUKA, Takashi ISHIDUKA, Riichi TAKAHASHI,
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Abstract(in English) The comb-type copolymer composed of poly(ethylene glycol) (PEG) and py (Py) or bipyridine (BPy) has been synthesized by RAFT polymerization. The obtained PEG-co-Py or Bpy was confirmed to coordinate with Pt (PEG-co-Bpy-Pt), which is characterized by IR, NMR, UV experiments. The multivalent interaction of the PEG-co-bpy-Pt with DNA was characterized and the cytotoxic effect of PEG-co-bpy-Pt on HeLa cells was estimated by MTT,depending on feed polymer concentration.
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Keyword(in English) comb-type copolymer / PEG / bipyridine / DNA
Paper # SDM2013-17,OME2013-17
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Committee OME
Conference Date 2013/4/18(1days)
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Registration To Organic Material Electronics (OME)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Biocompatible Comb-type Copolymer to form Self-assembled Monolayer
Sub Title (in English)
Keyword(1) comb-type copolymer
Keyword(2) PEG
Keyword(3) bipyridine
Keyword(4) DNA
1st Author's Name Hidenori OTSUKA
1st Author's Affiliation Department of Applied Chemistry, Faculty of Science, Tokyo University of Science()
2nd Author's Name Takashi ISHIDUKA
2nd Author's Affiliation Graduate School of Chemistry, Science and Technology, Tokyo University of Science
3rd Author's Name Riichi TAKAHASHI
3rd Author's Affiliation Graduate School of Chemistry, Science and Technology, Tokyo University of Science
Date 2013-04-26
Paper # SDM2013-17,OME2013-17
Volume (vol) vol.113
Number (no) 18
Page pp.pp.-
#Pages 4
Date of Issue