| Presentation | 2013-04-26 Fabrication of Chemical Modified Nanodiamond Particles for MRI Contrast Agents Takako NAKAMURA, Tsuguyori OHANA, Hajime YABUNO, Rumiko KASAI, Tetsuya SUZUKI, Terumitsu HASEBE, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We have developed a simple and useful process for fabricating nanodiamond (ND) particles modified with an organogadolinium moiety by chemical modification for their use as a magnetic resonance imaging (MRI) contrast agent. The introduction of the organogadolinium moiety on the surface of the ND particles was performed by the condensation of ND and diethylenetriaminepentaacetic acid (DTPA) followed by treatment with GdCl_3. The modified surfaces were evaluated by X-ray photoelectron spectroscopy, diffuse reflectance Fourier transform infrared spectroscopy, mass spectroscopy and inductively coupled plasma atomic emission spectroscopy analyses. MRI experiments on the Gd-DTPA-ND particles indicated their high signal intensity on T1-weighted images. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Nanodiamond particle / Chemical Modification / Gadolinium / MRI Contrast Agents |
| Paper # | SDM2013-12,OME2013-12 |
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| Conference Information | |
| Committee | OME |
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| Conference Date | 2013/4/18(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Organic Material Electronics (OME) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Fabrication of Chemical Modified Nanodiamond Particles for MRI Contrast Agents |
| Sub Title (in English) | |
| Keyword(1) | Nanodiamond particle |
| Keyword(2) | Chemical Modification |
| Keyword(3) | Gadolinium |
| Keyword(4) | MRI Contrast Agents |
| 1st Author's Name | Takako NAKAMURA |
| 1st Author's Affiliation | Advanced Manufacturing Research Institute, National Institute of Advanced Industrial Science and Technology() |
| 2nd Author's Name | Tsuguyori OHANA |
| 2nd Author's Affiliation | Advanced Manufacturing Research Institute, National Institute of Advanced Industrial Science and Technology |
| 3rd Author's Name | Hajime YABUNO |
| 3rd Author's Affiliation | Graduate School of Science and Technology, Keio University |
| 4th Author's Name | Rumiko KASAI |
| 4th Author's Affiliation | Toho University Sakura Medical Center |
| 5th Author's Name | Tetsuya SUZUKI |
| 5th Author's Affiliation | Graduate School of Science and Technology, Keio University |
| 6th Author's Name | Terumitsu HASEBE |
| 6th Author's Affiliation | School of Medicine, Tokai University |
| Date | 2013-04-26 |
| Paper # | SDM2013-12,OME2013-12 |
| Volume (vol) | vol.113 |
| Number (no) | 18 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |