| Presentation | 2013-01-24 Mouse MCG Measurement Using HTS-SQUID Takako MIZOGUCHI, Ruzo KAWABATA, Yusuke SEKI, Akihiko KANDORI, Akira TSUKAMOTO, Keiichi TANABE, Seiji ADACHI, Keiji ENPUKU, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | To predict drug safety variables, traditional cardiac testing for new drug has involved invasive examination using implanted electrode in small animals But today, alternative non-invasive methods have been developed because of high quality data derived from nonsurgical treatment of many animals The advantage of magnetocardiograph (MCG) is the non-invasiv measurement of cardiac physiological study Therefore, we have developed the HTS-SQUID system for non-invasively toxicological and safety study Then we have estimated the sensitivity of HTS-SQUID system and measured mice MCG As a result, the white noise level was measured as 8μΦ_0/√Hz using AC current bias Moreover, we could detect mice MCG and its magnetic field was 25 pT(p-p) Therefore the non-invasive approach, as the mouse MCG measurement, could be carried out under low-noise condition using our SQUID system |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | HTS-SQUID / MCG / Safety study / Drug development |
| Paper # | SCE2012-34 |
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| Conference Information | |
| Committee | SCE |
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| Conference Date | 2013/1/17(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Superconductive Electronics (SCE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Mouse MCG Measurement Using HTS-SQUID |
| Sub Title (in English) | |
| Keyword(1) | HTS-SQUID |
| Keyword(2) | MCG |
| Keyword(3) | Safety study |
| Keyword(4) | Drug development |
| 1st Author's Name | Takako MIZOGUCHI |
| 1st Author's Affiliation | Central Research Laboratory, Hitachi, Ltd() |
| 2nd Author's Name | Ruzo KAWABATA |
| 2nd Author's Affiliation | Central Research Laboratory, Hitachi, Ltd |
| 3rd Author's Name | Yusuke SEKI |
| 3rd Author's Affiliation | Central Research Laboratory, Hitachi, Ltd |
| 4th Author's Name | Akihiko KANDORI |
| 4th Author's Affiliation | Central Research Laboratory, Hitachi, Ltd |
| 5th Author's Name | Akira TSUKAMOTO |
| 5th Author's Affiliation | Superconductivity Research Laboratory, |
| 6th Author's Name | Keiichi TANABE |
| 6th Author's Affiliation | Superconductivity Research Laboratory, |
| 7th Author's Name | Seiji ADACHI |
| 7th Author's Affiliation | Superconductivity Research Laboratory, |
| 8th Author's Name | Keiji ENPUKU |
| 8th Author's Affiliation | Department of Electrical Engineering, Kyushu University |
| Date | 2013-01-24 |
| Paper # | SCE2012-34 |
| Volume (vol) | vol.112 |
| Number (no) | 408 |
| Page | pp.pp.- |
| #Pages | 5 |
| Date of Issue | |