| Presentation | 2012-06-28 Characteristics Prediction of Synaptic Modification in the Hippocampal CAl Network by Mutual information maximization Ryota MIYATA, Keisuke OTA, Toru AONISHI, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We employ a top-down approach to finding optimal neural implementations for executing a computation of the hippocampal CA1 network considered to function as a hetero-associative memory, and giving an implementation of computational roles of spike-timing-dependent plasticity (STDP). First, hypothesizing that the hippocampal CA1 network computationally works as the hetero-associative memory, we formulate a minimum model of memory functions as a phase reduction model consisting of a STDP window function and a phase response curve (PRC). Next, we analytically derive the mutual information between a stored phase memory pattern and a network output. By maximizing the mutual information, we search pairs of STDP window functions and PRCs optimally functioning as the hetero-associative memory. Here, we use PRCs of the hippocampal CA1 pyramidal neurons recorded in vitro, and under the constraint of measured PRCs, we search a set of optimal STDP window functions. A set of window functions we obtained qualitatively conform with various types of STDP reported previously. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | hippocampal CA1 pyramidal neuron / spike-timing-dependent plasticity / phase response curve / mutual information maximization / hetero-associative memory / oscillator associative memory model |
| Paper # | NC2012-10 |
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| Committee | NC |
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| Conference Date | 2012/6/21(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Characteristics Prediction of Synaptic Modification in the Hippocampal CAl Network by Mutual information maximization |
| Sub Title (in English) | |
| Keyword(1) | hippocampal CA1 pyramidal neuron |
| Keyword(2) | spike-timing-dependent plasticity |
| Keyword(3) | phase response curve |
| Keyword(4) | mutual information maximization |
| Keyword(5) | hetero-associative memory |
| Keyword(6) | oscillator associative memory model |
| 1st Author's Name | Ryota MIYATA |
| 1st Author's Affiliation | Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology:JSPS Research() |
| 2nd Author's Name | Keisuke OTA |
| 2nd Author's Affiliation | Brain Science Institute, RIKEN |
| 3rd Author's Name | Toru AONISHI |
| 3rd Author's Affiliation | Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology |
| Date | 2012-06-28 |
| Paper # | NC2012-10 |
| Volume (vol) | vol.112 |
| Number (no) | 108 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |