| Presentation | 2012-03-16 Computational simulation with detailed model neurons of suppression in orbitofrontal cortex during deep brain stimulation of the nucleus accumbens Keigo FUKUMOTO, Yuta KAKIMOTO, Osamu Araki, |
|---|---|
| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | This study examined inhibitory activity in the orbitofrontal cortex in response to deep brain stimulation targeted on nucleus accumbens and the parameter values such as its magnitude and period. We modeled pyramidal neurons and inhibitory neuron with GABAergic receptors and connected them with a nucleus accumbens model neuron. As a result of numerical experiments, larger magnitude and period, tends to induce higher inhibitory effect. And We understood that the state of GABAergic receptor affect to inhibitory activity on orbitofrontal cortex. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Deep Brain Stimulation / nucleus accumbens / orbitofrontal cortex / GABAergic receptor / model neurons |
| Paper # | MBE2011-146 |
| Date of Issue |
| Conference Information | |
| Committee | MBE |
|---|---|
| Conference Date | 2012/3/7(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | |
| Vice Chair | |
| Secretary | |
| Assistant | |
| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
|---|---|
| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Computational simulation with detailed model neurons of suppression in orbitofrontal cortex during deep brain stimulation of the nucleus accumbens |
| Sub Title (in English) | |
| Keyword(1) | Deep Brain Stimulation |
| Keyword(2) | nucleus accumbens |
| Keyword(3) | orbitofrontal cortex |
| Keyword(4) | GABAergic receptor |
| Keyword(5) | model neurons |
| 1st Author's Name | Keigo FUKUMOTO |
| 1st Author's Affiliation | Faculty of Science, Tokyo University of Science() |
| 2nd Author's Name | Yuta KAKIMOTO |
| 2nd Author's Affiliation | Faculty of Science, Tokyo University of Science |
| 3rd Author's Name | Osamu Araki |
| 3rd Author's Affiliation | Faculty of Science, Tokyo University of Science |
| Date | 2012-03-16 |
| Paper # | MBE2011-146 |
| Volume (vol) | vol.111 |
| Number (no) | 482 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |