Presentation 2012-03-16
In-vivo imaging analyses on the stimulation frequency dependence of signal transmission in the mouse visual cortex
Naohiro ISHIKAWA, Tamas FEHERVARI, Yuka OKAZAKI, Yuki HAYASHIDA, Tetsuya YAGI,
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Abstract(in English) In order to realize artificial vision by means of the cortical implant, it is critical to understand how the cortical responses evoked by electrical stimulation are transmitted to the higher-order visual areas. In the present study, we made analyses on the synaptic responses to electrical stimuli at the mouse primary visual cortex (V1) by the in-vivo imaging technique using a voltage-sensitive-dye, RH-1691. When a single pulse of the current stimulus was delivered through a glass microelectrode penetrating into the layer II/III of V1, a depolarizing response was induced around the stimulation site, and transmitted also to the higher-order visual areas. We found that such a signal transmissions can be modulated depending on the frequency of the repetitive pulse stimulation.
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Keyword(in English) Visual cortex / Signal transmission / Optical imaging / Repetitive pulse stimulation / Mouse
Paper # MBE2011-141
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Committee MBE
Conference Date 2012/3/7(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) In-vivo imaging analyses on the stimulation frequency dependence of signal transmission in the mouse visual cortex
Sub Title (in English)
Keyword(1) Visual cortex
Keyword(2) Signal transmission
Keyword(3) Optical imaging
Keyword(4) Repetitive pulse stimulation
Keyword(5) Mouse
1st Author's Name Naohiro ISHIKAWA
1st Author's Affiliation Graduate School of Engineering, Osaka Univ.()
2nd Author's Name Tamas FEHERVARI
2nd Author's Affiliation Graduate School of Engineering, Osaka Univ.
3rd Author's Name Yuka OKAZAKI
3rd Author's Affiliation Department of Rehabilitation Science, Osaka Health Science Univ.
4th Author's Name Yuki HAYASHIDA
4th Author's Affiliation Graduate School of Engineering, Osaka Univ.
5th Author's Name Tetsuya YAGI
5th Author's Affiliation Graduate School of Engineering, Osaka Univ.
Date 2012-03-16
Paper # MBE2011-141
Volume (vol) vol.111
Number (no) 482
Page pp.pp.-
#Pages 4
Date of Issue