Presentation 2012-03-15
Fundamental study for 3D reconstruction of fluorescent object in biological body
Eiji TOZAWA, Takeshi NAMITA, Yuji KATO, Koichi SHIMIZU,
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Abstract(in English) To improve the transcutaneous fluorescent image of an animal body, we derived the depth dependent point-spread function (PSF) for the fluorescent object in scattering medium and demonstrated scattering suppression technique using the depth dependent PSF. We have newly developed a technique to reconstruct 3-dimentional image of a fluorescent object using this scattering suppression technique and the common 2-dimentional tomography technique. The validity of the proposed technique was verified in simulation and experiment with model phantom. A PSF at a cylindrical surface of a diffuse scattering medium was also newly developed. The validity of this PSF and the applicability of this PSF to reconstruct the 3-dimensional image were verified in experiments.
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Keyword(in English) fluorescent imaging / point-spread function(PSF) / deconvolution / 3-dimentional reconstruction
Paper # MBE2011-130
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Conference Information
Committee MBE
Conference Date 2012/3/7(1days)
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Paper Information
Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Fundamental study for 3D reconstruction of fluorescent object in biological body
Sub Title (in English)
Keyword(1) fluorescent imaging
Keyword(2) point-spread function(PSF)
Keyword(3) deconvolution
Keyword(4) 3-dimentional reconstruction
1st Author's Name Eiji TOZAWA
1st Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University()
2nd Author's Name Takeshi NAMITA
2nd Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
3rd Author's Name Yuji KATO
3rd Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
4th Author's Name Koichi SHIMIZU
4th Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
Date 2012-03-15
Paper # MBE2011-130
Volume (vol) vol.111
Number (no) 482
Page pp.pp.-
#Pages 6
Date of Issue