Presentation 2012-03-14
Development of size distribution estimation technique for small, dense LDL in dynamic light scattering measurement
Dingding Wei, Takeshi Namita, Yuji Kato, Koichi Shimizu,
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Abstract(in English) A dynamic light scattering (DLS) technique has been applied to quantify the amount of the small dense low-density lipoprotein (sdLDL) which is clinically significant for coronary diseases. A technique to obtain the size distribution of LDL particles in the DLS measurement was newly developed. This technique is applicable even to the relatively narrow size-range (20-30 nm) of sdLDL, and vulnerable against the random noise in the autocorrelation function of DLS. The effectiveness of the proposed technique was verified in the computer simulation and in the experiment with latex spheres and LDL particles.
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Keyword(in English) small dense LDL / dynamic light scattering / size distribution estimation / nano-particles / inverse scattering problem
Paper # MBE2011-110
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Conference Information
Committee MBE
Conference Date 2012/3/7(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language ENG
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Development of size distribution estimation technique for small, dense LDL in dynamic light scattering measurement
Sub Title (in English)
Keyword(1) small dense LDL
Keyword(2) dynamic light scattering
Keyword(3) size distribution estimation
Keyword(4) nano-particles
Keyword(5) inverse scattering problem
1st Author's Name Dingding Wei
1st Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University()
2nd Author's Name Takeshi Namita
2nd Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
3rd Author's Name Yuji Kato
3rd Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
4th Author's Name Koichi Shimizu
4th Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
Date 2012-03-14
Paper # MBE2011-110
Volume (vol) vol.111
Number (no) 482
Page pp.pp.-
#Pages 6
Date of Issue