Presentation 2012-01-28
Frequency "Dependent Effects on ERP P300 by Repetitive Transcranial Magnetic Stimulation
Aya SATO, Tetsuya TORII, Masakuni IWAHASHI, Keiji IRAMINA,
PDF Download Page PDF download Page Link
Abstract(in Japanese) (See Japanese page)
Abstract(in English) The present study analyzed the effects of repetitive transcranial magnetic stimulation (rTMS) on brain activity. P300 latency of event-related potential (ERP) was used to evaluate the effect of low-frequency and short-term rTMS by SMG (supramarginal gyrus) and DLPFC (dorsolateral prefrontal cortex), which is considered to be the related area of P300 origin. A figure-eight coil was used to stimulate left-right SMG and left-right DLPFC, and the intensity of magnetic stimulation was 80% of subject's motor threshold. A total of 100-magnetic pulses were applied for rTMS. The effects of stimulus frequency at 1 or 0.5 Hz were determined. Following rTMS, the odd-ball task was performed and P300 latency of ERP was measured. ERP was measured prior to magnetic stimulation as a control. With 1 Hz low-frequency magnetic stimulation to the left SMG, P300 latency decreased. Compared to the control, the latency time difference was approximately 25 ms at Cz. In contrast, 0.5 Hz rTMS resulted in delayed P300 latency. Compared to the control, the latency time difference was approximately 17 ms at Cz. With 1-Hz low-frequency magnetic stimulation to the left DLPFC, P300 latency increased. Compared to the control, the latency time difference was approximately 26 ms at Cz. In contrast, 0.5 Hz rTMS resulted in maintained P300 latency. However, with sham at 1 or 0.5 Hz rTMS, the change of P300 latency wasn't observed. As a result, P300 latency was varied according to rTMS frequency and rTMS stimulation point.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) repetitive transcranial magnetic stimulation / supramarginal gyrus / dorsolateral prefrontal cortex / event-related potential / P300 latency / frequency-dependent
Paper # MBE2011-94
Date of Issue

Conference Information
Committee MBE
Conference Date 2012/1/20(1days)
Place (in Japanese) (See Japanese page)
Place (in English)
Topics (in Japanese) (See Japanese page)
Topics (in English)
Chair
Vice Chair
Secretary
Assistant

Paper Information
Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Frequency "Dependent Effects on ERP P300 by Repetitive Transcranial Magnetic Stimulation
Sub Title (in English)
Keyword(1) repetitive transcranial magnetic stimulation
Keyword(2) supramarginal gyrus
Keyword(3) dorsolateral prefrontal cortex
Keyword(4) event-related potential
Keyword(5) P300 latency
Keyword(6) frequency-dependent
1st Author's Name Aya SATO
1st Author's Affiliation Faculty of Health Sciences, Junshin Gakuen University()
2nd Author's Name Tetsuya TORII
2nd Author's Affiliation Faculty of Health Sciences, Junshin Gakuen University
3rd Author's Name Masakuni IWAHASHI
3rd Author's Affiliation Faculty of Health Sciences, Junshin Gakuen University
4th Author's Name Keiji IRAMINA
4th Author's Affiliation Graduate School of Systems Life Sciences, Kyushu University
Date 2012-01-28
Paper # MBE2011-94
Volume (vol) vol.111
Number (no) 423
Page pp.pp.-
#Pages 5
Date of Issue