| Presentation | 2011-11-24 Spatio-temporal properties of spike initiation in response to electric stimuli in an auditory nerve fiber model with stochastic ion channels Hiroyuki MINO, Parichat KUMSA, Hiroki ARATA, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Cochlear implant is a technology which allows deaf people to hear sounds with electrical stimulations. In this report, spatio-temporal properties of spike initiation in response to electric stimuli are invesitgated in an auditory nerve fiber with stochastic sodium and potassium channels through computer simulations. This kind of properties is exclusively performed through computer simulations, unlike animal experiments. The results of computer simulations show that spike initiations in response to a single pulsatile electric stimlus are randmized spatially and temporally as the electrode-to-fiber increases. Likewise, it is shown that spike initiations in response to the second pulssatile stimulus in a paired two pulse stimulus situation are more distributed spatially and temporally, compared with those of a single pulse stimulus, implying the influences of refractory properties on the randmization of spike initiations. In conclusion, the randmness or fluctuation of spike initiations in response to pulsatile electric stimuli plays an important role in designing stimulus waveforms. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Electrical stimulation / Temporal spike jitter / Stochastic Hodgkin-Huxley model |
| Paper # | MBE2011-61 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2011/11/17(1days) |
| Place (in Japanese) | (See Japanese page) |
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| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Spatio-temporal properties of spike initiation in response to electric stimuli in an auditory nerve fiber model with stochastic ion channels |
| Sub Title (in English) | |
| Keyword(1) | Electrical stimulation |
| Keyword(2) | Temporal spike jitter |
| Keyword(3) | Stochastic Hodgkin-Huxley model |
| 1st Author's Name | Hiroyuki MINO |
| 1st Author's Affiliation | College of Engineering, Kanto Gakuin University() |
| 2nd Author's Name | Parichat KUMSA |
| 2nd Author's Affiliation | College of Engineering, Kanto Gakuin University |
| 3rd Author's Name | Hiroki ARATA |
| 3rd Author's Affiliation | College of Engineering, Kanto Gakuin University |
| Date | 2011-11-24 |
| Paper # | MBE2011-61 |
| Volume (vol) | vol.111 |
| Number (no) | 314 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |