Presentation 2011/6/16
Model-based identification of synaptic connectivity from multi-neuronal spike train data
JUNICHIRO YOSHIMOTO, KENJI DOYA,
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Abstract(in English) The paper presents a method to identify synaptic connectivity from multineuronal spike train data. In this method, a stochastic spiking neural network model is derived on the basis of generalized leaky integrate-and-fire neurons connected with multi-exponential post-synaptic current function. The model parameters are fitted based on maximum likelihood estimation and a sparse Bayesian framework. Then, the model is employed to quantify how much a spike of the pre-neuron changes the potential of the post-neuron. Based on the quantities, the synaptic connectivity between two neurons are identified. The basic performance was demonstrated by applying the method to two synthetic benchmarks. The results showed that the method was able to identify the synaptic connectivity in the benchmarks with a high precision.
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Paper # Vol.2011-BIO-25 No.4
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Committee NC
Conference Date 2011/6/16(1days)
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Registration To Neurocomputing (NC)
Language JPN
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Title (in English) Model-based identification of synaptic connectivity from multi-neuronal spike train data
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1st Author's Name JUNICHIRO YOSHIMOTO
1st Author's Affiliation Neural Computation Unit, Okinawa Institute of Science and Technology:Graduate School of Information Science, Nara Institute of Science and Technology()
2nd Author's Name KENJI DOYA
2nd Author's Affiliation Neural Computation Unit, Okinawa Institute of Science and Technology:Graduate School of Information Science, Nara Institute of Science and Technology
Date 2011/6/16
Paper # Vol.2011-BIO-25 No.4
Volume (vol) vol.111
Number (no) 96
Page pp.pp.-
#Pages 6
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