Presentation 2011-06-23
Difference of information processing between two dendrite locations in the hippocampal granule cells
Hirofumi HAYAKAWA, Tadanobu KAMIJO, Yasuhiro FUKUSHIMA, Takeshi AIHARA,
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Abstract(in English) Dentate gyrus granule cells in hippocampus have the input though the lateral perforant path (LPP) with non-spatial information, smell etc., and the input though the medial perforant path (MPP) with spatial information, place. Inputs, though the LPP, from layer II in the entorhinal cortex (EC) to the lateral dendrite (LD) of dentate granule cells and those, though the MPP, are projected to the medial dendrite (MD), respectively. Recently, the hippocampal-dependent declarative memory was reported in humans. It indicated that the non-spatial information, smell, influenced on the processing of the spatial information, place. Therefore, there is a possibility that the processing of spatial information is influenced by non-specific information in dentate granule. In this study, clarify how spatial information and non-spatial information are integrated using electrophysiological experiment, and show the mechanism by a simulation experiment.
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Keyword(in English) hippocampus / dentate gyrus / granule cell / dendrite / information processing
Paper # NC2011-3
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Committee NC
Conference Date 2011/6/16(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Difference of information processing between two dendrite locations in the hippocampal granule cells
Sub Title (in English)
Keyword(1) hippocampus
Keyword(2) dentate gyrus
Keyword(3) granule cell
Keyword(4) dendrite
Keyword(5) information processing
1st Author's Name Hirofumi HAYAKAWA
1st Author's Affiliation Graduate School of Engineering, Tamagawa University()
2nd Author's Name Tadanobu KAMIJO
2nd Author's Affiliation Graduate School of Brain Sciences, Tamagawa University
3rd Author's Name Yasuhiro FUKUSHIMA
3rd Author's Affiliation Brain Science Institute, Tamagawa University
4th Author's Name Takeshi AIHARA
4th Author's Affiliation Graduate School of Engineering, Tamagawa University:Graduate School of Brain Sciences, Tamagawa University:Brain Science Institute, Tamagawa University
Date 2011-06-23
Paper # NC2011-3
Volume (vol) vol.111
Number (no) 96
Page pp.pp.-
#Pages 5
Date of Issue