Presentation 2011-01-20
Brain Shape Normalization in Neonatal Brain MR Images
Aya HASHIOKA, Syoji KOBASHI, Kei KURAMOTO, Yuki WAKATA, Kumiko ANDO, Reiichi ISHIKURA, Tomomoto ISHIKAWA, Shozo HIROTA, Yutaka HATA,
PDF Download Page PDF download Page Link
Abstract(in Japanese) (See Japanese page)
Abstract(in English) In order to diagnose the cerebral diseases in the early stage, diagnosing method for neonatal brain must be studied. Voxel-based morphometry (VBM) is an approach to diagnose the cerebral diseases using MR (magnetic resonance) images. VBM normalizes the evaluating brain MR images into a template, and evaluates the distribution of gray matter density statistically. Because the template is produced from adult brain MR images, it is difficult to apply the conventional normalization to the neonatal brain. In this article, three new normalization approaches for the neonatal brain are proposed. The 1st approach defines an individual neonatal brain as a template. The 2nd approach introduces skull stripping into the 1st approach. The 3rd approach produces a neonatal template brain from some neonatal brains. Normalization accuracy was evaluated by using mutual information, position of anterior and posterior commissures (AC and PC) and angle of AC-PC line. The results in 14 neonates (revised age between -4 and 4 weeks) showed that the normalization accuracy of the 3rd approach was significantly higher than the conventional normalization and the other two approaches.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) voxel-based morphometry / MR image / neonate / brain / template / normalization / mutual information / anterior commissure / posterior commisure
Paper # MI2010-103
Date of Issue

Conference Information
Committee MI
Conference Date 2011/1/12(1days)
Place (in Japanese) (See Japanese page)
Place (in English)
Topics (in Japanese) (See Japanese page)
Topics (in English)
Chair
Vice Chair
Secretary
Assistant

Paper Information
Registration To Medical Imaging (MI)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Brain Shape Normalization in Neonatal Brain MR Images
Sub Title (in English)
Keyword(1) voxel-based morphometry
Keyword(2) MR image
Keyword(3) neonate
Keyword(4) brain
Keyword(5) template
Keyword(6) normalization
Keyword(7) mutual information
Keyword(8) anterior commissure
Keyword(9) posterior commisure
1st Author's Name Aya HASHIOKA
1st Author's Affiliation University of Hyogo()
2nd Author's Name Syoji KOBASHI
2nd Author's Affiliation Graduate School of Engineering, University of Hyogo:WPI Immunology Frontier Research Center, Osaka University
3rd Author's Name Kei KURAMOTO
3rd Author's Affiliation Graduate School of Engineering, University of Hyogo:WPI Immunology Frontier Research Center, Osaka University
4th Author's Name Yuki WAKATA
4th Author's Affiliation Hyogo College of Medicine
5th Author's Name Kumiko ANDO
5th Author's Affiliation Hyogo College of Medicine
6th Author's Name Reiichi ISHIKURA
6th Author's Affiliation Hyogo College of Medicine
7th Author's Name Tomomoto ISHIKAWA
7th Author's Affiliation Ishikawa Hospital
8th Author's Name Shozo HIROTA
8th Author's Affiliation Hyogo College of Medicine
9th Author's Name Yutaka HATA
9th Author's Affiliation Graduate School of Engineering, University of Hyogo:WPI Immunology Frontier Research Center, Osaka University
Date 2011-01-20
Paper # MI2010-103
Volume (vol) vol.110
Number (no) 364
Page pp.pp.-
#Pages 6
Date of Issue