Presentation | 2011-01-20 Brain Shape Normalization in Neonatal Brain MR Images Aya HASHIOKA, Syoji KOBASHI, Kei KURAMOTO, Yuki WAKATA, Kumiko ANDO, Reiichi ISHIKURA, Tomomoto ISHIKAWA, Shozo HIROTA, Yutaka HATA, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | In order to diagnose the cerebral diseases in the early stage, diagnosing method for neonatal brain must be studied. Voxel-based morphometry (VBM) is an approach to diagnose the cerebral diseases using MR (magnetic resonance) images. VBM normalizes the evaluating brain MR images into a template, and evaluates the distribution of gray matter density statistically. Because the template is produced from adult brain MR images, it is difficult to apply the conventional normalization to the neonatal brain. In this article, three new normalization approaches for the neonatal brain are proposed. The 1st approach defines an individual neonatal brain as a template. The 2nd approach introduces skull stripping into the 1st approach. The 3rd approach produces a neonatal template brain from some neonatal brains. Normalization accuracy was evaluated by using mutual information, position of anterior and posterior commissures (AC and PC) and angle of AC-PC line. The results in 14 neonates (revised age between -4 and 4 weeks) showed that the normalization accuracy of the 3rd approach was significantly higher than the conventional normalization and the other two approaches. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | voxel-based morphometry / MR image / neonate / brain / template / normalization / mutual information / anterior commissure / posterior commisure |
Paper # | MI2010-103 |
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Conference Information | |
Committee | MI |
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Conference Date | 2011/1/12(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | Medical Imaging (MI) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Brain Shape Normalization in Neonatal Brain MR Images |
Sub Title (in English) | |
Keyword(1) | voxel-based morphometry |
Keyword(2) | MR image |
Keyword(3) | neonate |
Keyword(4) | brain |
Keyword(5) | template |
Keyword(6) | normalization |
Keyword(7) | mutual information |
Keyword(8) | anterior commissure |
Keyword(9) | posterior commisure |
1st Author's Name | Aya HASHIOKA |
1st Author's Affiliation | University of Hyogo() |
2nd Author's Name | Syoji KOBASHI |
2nd Author's Affiliation | Graduate School of Engineering, University of Hyogo:WPI Immunology Frontier Research Center, Osaka University |
3rd Author's Name | Kei KURAMOTO |
3rd Author's Affiliation | Graduate School of Engineering, University of Hyogo:WPI Immunology Frontier Research Center, Osaka University |
4th Author's Name | Yuki WAKATA |
4th Author's Affiliation | Hyogo College of Medicine |
5th Author's Name | Kumiko ANDO |
5th Author's Affiliation | Hyogo College of Medicine |
6th Author's Name | Reiichi ISHIKURA |
6th Author's Affiliation | Hyogo College of Medicine |
7th Author's Name | Tomomoto ISHIKAWA |
7th Author's Affiliation | Ishikawa Hospital |
8th Author's Name | Shozo HIROTA |
8th Author's Affiliation | Hyogo College of Medicine |
9th Author's Name | Yutaka HATA |
9th Author's Affiliation | Graduate School of Engineering, University of Hyogo:WPI Immunology Frontier Research Center, Osaka University |
Date | 2011-01-20 |
Paper # | MI2010-103 |
Volume (vol) | vol.110 |
Number (no) | 364 |
Page | pp.pp.- |
#Pages | 6 |
Date of Issue |