| Presentation | 2011-01-20 Preliminary study of in-vivo liver measurement by optimized pulse sequence for MR elastography Ken ARAI, Mikio SUGA, Shinya OZAWA, Hajime IKEDA, Masaya HIRANO, Etsuko KOBAYASHI, Takayuki OBATA, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Magnetic resonance elastography (MRE) is a technique for quantitative and noninvasive assessment of tissue elasticity. MRE is often described as image-based palpation that can be used to characterize disease because the mechanical properties of tissues are often dramatically affected by the presence of disease processes. MRE pulse sequences obtain shear wave images by synchronizing motion sensitized gradients (MSG) with an external vibrator. A quantitative shear modulus map is calculated from the shear wave images. However, the magnitude property of the external vibrator and nonlinearity of the imaged object often induce unwanted higher harmonics that distort the shear wave images and impair estimation errors to the elastic modulus. Additionally, bulk motion can induce signal loss, ghosting and unwanted phase accumulation. In this study, we apply gradient moment nulling (GMN) to the MSG for reducing bulk motion effect to the shear wave images. The MSGs were optimized to minimize the contribution of higher harmonics therefore deteriorate the accuracy of elastic modulus estimation. In-vivo study was performed to confirm the performance of the proposed MRE pulse sequence. The proposed MRE pulse sequence reduced cardiac motion artifact. The acquired elastograms suggest that the optimized MSG is able to acquire accurate elastic modulus. These results show that the proposed pulse sequence might be useful for in-vivo MRE studies. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | MR elastography / pulse sequence / motion sensitized gradient / gradient moment nulling / elastic modulus |
| Paper # | MI2010-89 |
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| Conference Information | |
| Committee | MI |
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| Conference Date | 2011/1/12(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Medical Imaging (MI) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Preliminary study of in-vivo liver measurement by optimized pulse sequence for MR elastography |
| Sub Title (in English) | |
| Keyword(1) | MR elastography |
| Keyword(2) | pulse sequence |
| Keyword(3) | motion sensitized gradient |
| Keyword(4) | gradient moment nulling |
| Keyword(5) | elastic modulus |
| 1st Author's Name | Ken ARAI |
| 1st Author's Affiliation | Chiba University() |
| 2nd Author's Name | Mikio SUGA |
| 2nd Author's Affiliation | Chiba University:National Institute of Radiological Sciences |
| 3rd Author's Name | Shinya OZAWA |
| 3rd Author's Affiliation | Chiba University |
| 4th Author's Name | Hajime IKEDA |
| 4th Author's Affiliation | Chiba University |
| 5th Author's Name | Masaya HIRANO |
| 5th Author's Affiliation | GE Healthcare Japan Corporation |
| 6th Author's Name | Etsuko KOBAYASHI |
| 6th Author's Affiliation | The University of Tokyo |
| 7th Author's Name | Takayuki OBATA |
| 7th Author's Affiliation | National Institute of Radiological Sciences |
| Date | 2011-01-20 |
| Paper # | MI2010-89 |
| Volume (vol) | vol.110 |
| Number (no) | 364 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |