Presentation 2010-11-19
Distribution of oxygen consumption in cardiac tissue with micro circulation simulation
Yoshiaki AKAJI, Yuuta KUBOTA, Takao SHIMAYOSHI, Akira AMANO, Tetsuya MATSUDA,
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Abstract(in English) To understand conditions under cardiac ischemia or hypoxia, it is of importance to evaluate oxygen consumption in the myocardial microcirculation. However, there are difficulties in accurate measurements of the oxygen consumption experimentlly. Therefore, computer simulation is an important methodology to evaluate the oxygen consumption. For simulation of oxygen consumption in a cardiac tissue, a myocardial microcirculation model is proposed in this report. The model couples a tissue microcirculation model and a myocardial cell model. The simulation results under low oxygen conditions of the arterial blood show that oxygen consumptions decrease from the arterial side to the venous side and that cells in the venous side are under hypoxia.
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Keyword(in English) microcirculation / oxygen consumption / hypoxia / myocardial cell model / biodynamics simulation
Paper # MBE2010-51
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Committee MBE
Conference Date 2010/11/11(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Distribution of oxygen consumption in cardiac tissue with micro circulation simulation
Sub Title (in English)
Keyword(1) microcirculation
Keyword(2) oxygen consumption
Keyword(3) hypoxia
Keyword(4) myocardial cell model
Keyword(5) biodynamics simulation
1st Author's Name Yoshiaki AKAJI
1st Author's Affiliation Graduate School of Informatics, Kyoto University()
2nd Author's Name Yuuta KUBOTA
2nd Author's Affiliation Graduate School of Informatics, Kyoto University
3rd Author's Name Takao SHIMAYOSHI
3rd Author's Affiliation ASTEM Research Institute of Kyoto
4th Author's Name Akira AMANO
4th Author's Affiliation College of Life Sciences, Ritsumeikan University
5th Author's Name Tetsuya MATSUDA
5th Author's Affiliation Graduate School of Informatics, Kyoto University
Date 2010-11-19
Paper # MBE2010-51
Volume (vol) vol.110
Number (no) 294
Page pp.pp.-
#Pages 5
Date of Issue