| Presentation | 2010-11-18 Role of acetylcholine on change of auditory brainstem responses during sleep Takahiro FUKASAWA, Hirofumi OKUBO, Akihiro KARASHIMA, Norihiro KATAYAMA, Mitsuyuki NAKAO, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Although auditory evoked response (ABR) was considered to be insensitive to physiological sleep, we found that amplitude of the ABR increases during NREM sleep. In this study, effect of carbachol, which activates muscarinic receptor, on amplitude of the ABR was examined to show the role of acetylcholine in the sleep-wake state dependency of ABR amplitude. Amplitude of ABR wave IV was found to decrease just after the injection of carbachol into the lateral ventricle. Because acetylcholine concentration is high during wakefulness, these results suggest that acetylcholine plays a crucial role in the attenuation of ABR during wakefulness. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Auditory brainstem responses / Acetylcholine / Sleep-wake state |
| Paper # | MBE2010-37 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2010/11/11(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Role of acetylcholine on change of auditory brainstem responses during sleep |
| Sub Title (in English) | |
| Keyword(1) | Auditory brainstem responses |
| Keyword(2) | Acetylcholine |
| Keyword(3) | Sleep-wake state |
| 1st Author's Name | Takahiro FUKASAWA |
| 1st Author's Affiliation | Biomodeling Laboratory, Graduate School of Information Sciences Tohoku University() |
| 2nd Author's Name | Hirofumi OKUBO |
| 2nd Author's Affiliation | Biomodeling Laboratory, Graduate School of Information Sciences Tohoku University |
| 3rd Author's Name | Akihiro KARASHIMA |
| 3rd Author's Affiliation | Biomodeling Laboratory, Graduate School of Information Sciences Tohoku University |
| 4th Author's Name | Norihiro KATAYAMA |
| 4th Author's Affiliation | Biomodeling Laboratory, Graduate School of Information Sciences Tohoku University |
| 5th Author's Name | Mitsuyuki NAKAO |
| 5th Author's Affiliation | Biomodeling Laboratory, Graduate School of Information Sciences Tohoku University |
| Date | 2010-11-18 |
| Paper # | MBE2010-37 |
| Volume (vol) | vol.110 |
| Number (no) | 294 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |