| Presentation | 2010-03-09 Morphology dependence of the passive membrane potential response of a neuron for alternating extracellular electric field Satoru AOYAMA, Toshiaki OHMORI, Toru AONISHI, Masashi INOUE, Hiroyoshi MIYAKAWA, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Previously we reported that, in response to an applied extracellular DC field, the membrane potential near the soma changes with slow time course, and the potential in the apical dendrites shows biphasic change with with fast and slow time course. For AC field, the potential in the apical dendrites shows frequency dependent changes. In our recent modeling studies, we have shown that a leaky cable model with low membrane resistivity on one end mimics these behaviors. As an alternative account for the experimental results, we tested the impact of the morphology of the cells for DC field induced responses, and found that the morphology for AC field by performing compartmental model simulations, to find that the morphology also can account for the frequency dependent behavior of the dendrites. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | CA1 pyramidal cell / Extracellular electric field / Morphology of a neuron / Compartmental modeling |
| Paper # | NC2009-103 |
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| Conference Information | |
| Committee | NC |
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| Conference Date | 2010/3/2(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Morphology dependence of the passive membrane potential response of a neuron for alternating extracellular electric field |
| Sub Title (in English) | |
| Keyword(1) | CA1 pyramidal cell |
| Keyword(2) | Extracellular electric field |
| Keyword(3) | Morphology of a neuron |
| Keyword(4) | Compartmental modeling |
| 1st Author's Name | Satoru AOYAMA |
| 1st Author's Affiliation | Lab. Cellular Neurobiology, Tokyo Univ. Pharmacy and Life Science() |
| 2nd Author's Name | Toshiaki OHMORI |
| 2nd Author's Affiliation | Univ. of Tokyo, Chiba, Japan & RIKEN BSI |
| 3rd Author's Name | Toru AONISHI |
| 3rd Author's Affiliation | Tokyo Inst. Tach. |
| 4th Author's Name | Masashi INOUE |
| 4th Author's Affiliation | Lab. Cellular Neurobiology, Tokyo Univ. Pharmacy and Life Science |
| 5th Author's Name | Hiroyoshi MIYAKAWA |
| 5th Author's Affiliation | Lab. Cellular Neurobiology, Tokyo Univ. Pharmacy and Life Science |
| Date | 2010-03-09 |
| Paper # | NC2009-103 |
| Volume (vol) | vol.109 |
| Number (no) | 461 |
| Page | pp.pp.- |
| #Pages | 6 |
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