| Presentation | 2010-03-09 Estimation of Intracellular Calcium Ion Dynamics by Particle Filter Application for Actual Physiological Experimental Data Takamasa TSUNODA, Toshiaki OMORI, Hiroyoshi MIYAKAWA, Masato OKADA, Toru AONISHI, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Recently, some statistical methods for estimating Ca^<2+> concentration from fluorescent signals of Ca^<2+> indicator dyes have been proposed. These statistical models are characterized by the parametric indefiniteness in common. In this paper, we propose a state space model with a hierarchical Bayes structure. We introduce hyperpriors for generating parameters of the state space model, resulting in the parametric uniqueness. We implement this hierarchical Bayes model with the particle filter method, and by applying to artificial and real fluorescent signals, we verify the effectiveness of the proposed method. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | intracellular Ca^<2+> concentration / Calcium imaging / Nonlinear state space model / Particle filter / Hierarchical Bayes |
| Paper # | NC2009-96 |
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| Committee | NC |
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| Conference Date | 2010/3/2(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Estimation of Intracellular Calcium Ion Dynamics by Particle Filter Application for Actual Physiological Experimental Data |
| Sub Title (in English) | |
| Keyword(1) | intracellular Ca^<2+> concentration |
| Keyword(2) | Calcium imaging |
| Keyword(3) | Nonlinear state space model |
| Keyword(4) | Particle filter |
| Keyword(5) | Hierarchical Bayes |
| 1st Author's Name | Takamasa TSUNODA |
| 1st Author's Affiliation | Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology() |
| 2nd Author's Name | Toshiaki OMORI |
| 2nd Author's Affiliation | Graduate School of Frontier Sciences, The University of Tokyo:RIKEN Brain Science Institute |
| 3rd Author's Name | Hiroyoshi MIYAKAWA |
| 3rd Author's Affiliation | School of Life Science, Tokyo University of Pharmacy and Life Science |
| 4th Author's Name | Masato OKADA |
| 4th Author's Affiliation | Graduate School of Frontier Sciences, The University of Tokyo:RIKEN Brain Science Institute |
| 5th Author's Name | Toru AONISHI |
| 5th Author's Affiliation | Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology:RIKEN Brain Science Institute |
| Date | 2010-03-09 |
| Paper # | NC2009-96 |
| Volume (vol) | vol.109 |
| Number (no) | 461 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |