Presentation 2010-06-24
US2010-22 Study to trap higher amount of microbubbles in flow through various conditions of local acoustic radiation force
Ryusuke Nakamoto, Yuto Taguchi, Toshikazu Kato, Nobuyuki Watarai, Ren Koda, Takashi Yoshinaga, Kohji Masuda,
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Abstract(in English) We have ever proposed a physical DDS (Drug Delivery System) by making use of the microbubbles of inn order, which have a possibility to contain the specified drug and also are easily affected under ultrasound emission near their resonant frequency. Also the feature to use the bubbles is easily detected and actuated by ultrasound. However, because of the diffusion of bubbles after injection inside human body, it was difficult to enhance the efficiency of medication in the disease part. So we tried to trap the fluid bubbles by using local acoustic radiation force. We have observed that the bubbles were trapped in an artificial blood vessel, to evaluate the effect of acoustic radiation force. The trapped area of bubbles was increased according to amplitude, emission time of ultrasound and was decreased according to frequency. From those results, we derived optimal conditions to trap the bubbles.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) DDS / Microbubble / Acoustic radiation force / Trapping
Paper # US2010-22
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Committee US
Conference Date 2010/6/17(1days)
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Registration To Ultrasonics (US)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) US2010-22 Study to trap higher amount of microbubbles in flow through various conditions of local acoustic radiation force
Sub Title (in English)
Keyword(1) DDS
Keyword(2) Microbubble
Keyword(3) Acoustic radiation force
Keyword(4) Trapping
1st Author's Name Ryusuke Nakamoto
1st Author's Affiliation School of Bio-Applications & Systems Engineering, Tokyo Univ. A&T()
2nd Author's Name Yuto Taguchi
2nd Author's Affiliation School of Bio-Applications & Systems Engineering, Tokyo Univ. A&T
3rd Author's Name Toshikazu Kato
3rd Author's Affiliation School of Bio-Applications & Systems Engineering, Tokyo Univ. A&T
4th Author's Name Nobuyuki Watarai
4th Author's Affiliation School of Bio-Applications & Systems Engineering, Tokyo Univ. A&T
5th Author's Name Ren Koda
5th Author's Affiliation Graduate School of Advanced Integration Science, Chiba Univ.
6th Author's Name Takashi Yoshinaga
6th Author's Affiliation School of Bio-Applications & Systems Engineering, Tokyo Univ. A&T
7th Author's Name Kohji Masuda
7th Author's Affiliation School of Bio-Applications & Systems Engineering, Tokyo Univ. A&T
Date 2010-06-24
Paper # US2010-22
Volume (vol) vol.110
Number (no) 91
Page pp.pp.-
#Pages 5
Date of Issue