Presentation 2010/3/19
Environmental Hormones : The endocrine disruptors, toxic compounds which interfere with the signal transductions by competing with hormone to the receptors
Ikuko UENO,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) Since the discovery of insecticidal effect of DDT in the1930's a large amount of organic chlorinated compounds were used as pesticides in the field and industrial materials in the town. As the results environmental pollution, unusual reproduction and death occurred in the birds, fishes, other wild animals and poultry. Estrogenic action of DDT was demonstrated. These observations triggered the world-wide control of the public hazards. I will talk about the causes and the process of the endocrine disruptors' problems, correlation between molecular structure and toxic action of the 67compounds expecting to be endocrine disruptors, molecular mechanism and hormone receptor families of the endocrine disruptors, and others. The statement on the action of endocrine disruptors in human published June 2009 by U.S.A Endocrinological Society will be introduced.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Endocrine disrupting Chemicals / EDCs / Estrogen / Steroid hormone / receptor / DDT
Paper # SSS2009-30
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Conference Information
Committee SSS
Conference Date 2010/3/19(1days)
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Registration To Safety (SSS)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Environmental Hormones : The endocrine disruptors, toxic compounds which interfere with the signal transductions by competing with hormone to the receptors
Sub Title (in English)
Keyword(1) Endocrine disrupting Chemicals
Keyword(2) EDCs
Keyword(3) Estrogen
Keyword(4) Steroid hormone
Keyword(5) receptor
Keyword(6) DDT
1st Author's Name Ikuko UENO
1st Author's Affiliation The Medical Institute of Tokyo University:(Present office)Bioresearch Laboratory()
Date 2010/3/19
Paper # SSS2009-30
Volume (vol) vol.109
Number (no) 473
Page pp.pp.-
#Pages 6
Date of Issue