| Presentation | 2009-11-13 Multi-site recordings of synaptic responses in mouse thalamocortical slices Kaori ARAI, Norihiro KATAYAMA, Yasushi SHIRAISHI, Akihiro KARASHIMA, Mitsuyuki NAKAO, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | The rodent's whisker sensory information is transmitted to barrel cortex via ventral posteromedian nucleus (VPM) and posterior medial nucleus (POm) of thalamus. It is suggested that POm transmit whiskering sensation, and VPM transmit both whiskering and steady sensation. In this study, we investigate the spatio-temporal dynamics of barrel cortex in response to VPM stimulation using thalamocortical slice preparation of mice, in which thalamus, neocortex and thalamocortecal synaptic connections are kept alive. It is found that the successive two electical stimulation (paired pulse stimulation) to VPM with interval of less than 300-ms showed paired-pulse depression (PPD) of the response in the barrel cortex. The current source-density analysis suggests that the PPD occurrs at the synaptic transmission from VPM to layer 4 neuron in the barrel cortex. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | mouse / barrel cortex / thalamus / thalamocortical slice / thalamocortical synapse / paired-pulse depression |
| Paper # | MBE2009-62 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2009/11/5(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Multi-site recordings of synaptic responses in mouse thalamocortical slices |
| Sub Title (in English) | |
| Keyword(1) | mouse |
| Keyword(2) | barrel cortex |
| Keyword(3) | thalamus |
| Keyword(4) | thalamocortical slice |
| Keyword(5) | thalamocortical synapse |
| Keyword(6) | paired-pulse depression |
| 1st Author's Name | Kaori ARAI |
| 1st Author's Affiliation | Graduate School of Information sciences, Tohoku University() |
| 2nd Author's Name | Norihiro KATAYAMA |
| 2nd Author's Affiliation | Graduate School of Information sciences, Tohoku University |
| 3rd Author's Name | Yasushi SHIRAISHI |
| 3rd Author's Affiliation | Graduate School of Information sciences, Tohoku University |
| 4th Author's Name | Akihiro KARASHIMA |
| 4th Author's Affiliation | Graduate School of Information sciences, Tohoku University |
| 5th Author's Name | Mitsuyuki NAKAO |
| 5th Author's Affiliation | Graduate School of Information sciences, Tohoku University |
| Date | 2009-11-13 |
| Paper # | MBE2009-62 |
| Volume (vol) | vol.109 |
| Number (no) | 279 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |