| Presentation | 2009-10-29 Insolubilization of Chitosan by Ammonia : Study of Insolubilization Kouhei TANAKA, Toshiaki NAGAKURA, Naohiro YOSHIDA, Kazuki INADA, Yuto SUSUKI, Akira YAMADA, Masashi IKEUCHI, Koju IKUTA, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We study that the osmotic pressure valve system which supplies insulin automatically to diabetes patients, when the blood sugar level rises. The diaphragm of valve system opens and closes by osmotic pressure due to the change of the blood sugar level by a permeable film, the insulin is supplied automatically from reserver tank. This system does not need energy supply and a control system in this system. As for this structure, this valve system consisted of three parts. The housing part made from epoxy resin, which harden by UV laser, permeable film made by the cellulose acetate and diaphragm part was made by latex. When blood sugar level of outside of osmotic pressure valve rises, a solvent inside the housing begins to flow through a permeable film. This flow make transform diaphragm and open the valve. By animal experiment, we confirmed that insulin is injected in to the body by this osmotic pressure valve. We made this osmotic valve by epoxy resin. However, from the biocompatible standpoint, we tried to examine the osmotic valve can be made by the biocompatible material. Because it was vast natural resources, we chose this material as chitosan. This molecular structure resembles cellulose, and it is the materials that it is already applied to the medical field. Therefore it is necessary for making the osmotic valve system to insolubilize of chitosan solution. Because we studied quantitatively, we report the insolubilization method of the chitosan. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Chitosan / Osmtic valve / Diabetes / Insolubilization / Blood suger / Osmotic pressure |
| Paper # | MBE2009-58 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2009/10/22(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Insolubilization of Chitosan by Ammonia : Study of Insolubilization |
| Sub Title (in English) | |
| Keyword(1) | Chitosan |
| Keyword(2) | Osmtic valve |
| Keyword(3) | Diabetes |
| Keyword(4) | Insolubilization |
| Keyword(5) | Blood suger |
| Keyword(6) | Osmotic pressure |
| 1st Author's Name | Kouhei TANAKA |
| 1st Author's Affiliation | Department of Biomedical Engineering, Osaka Electro-Communication() |
| 2nd Author's Name | Toshiaki NAGAKURA |
| 2nd Author's Affiliation | Department of Biomedical Engineering, Osaka Electro-Communication |
| 3rd Author's Name | Naohiro YOSHIDA |
| 3rd Author's Affiliation | Graduate School of Applied Informations, University Hyogo |
| 4th Author's Name | Kazuki INADA |
| 4th Author's Affiliation | Graduate School of Applied Informations, University Hyogo |
| 5th Author's Name | Yuto SUSUKI |
| 5th Author's Affiliation | Osaka University Graduate School of Medicine, Division of Health Sciences |
| 6th Author's Name | Akira YAMADA |
| 6th Author's Affiliation | Cardiovascular Physiology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University |
| 7th Author's Name | Masashi IKEUCHI |
| 7th Author's Affiliation | Graduate School Engineering, School of Engineering Micro-Nano Systems Eng, Nagoya University |
| 8th Author's Name | Koju IKUTA |
| 8th Author's Affiliation | Graduate School Engineering, School of Engineering Micro-Nano Systems Eng, Nagoya University |
| Date | 2009-10-29 |
| Paper # | MBE2009-58 |
| Volume (vol) | vol.109 |
| Number (no) | 258 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |