| Presentation | 2009-05-29 Simulation studies on appropriate imaging parameters for diffusion weighted function MRI Shizue NAGAHARA, Takenori OIDA, Tetsuo KOBAYASI, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Recentry, it has become possible to mesure human brain functions by using noninvasive methods. Among these methods, functional MRI (fMRI) which is based on blood oxygenation level dependent (BOLD) contrast has been used most widely. In recent years, however, it has been reported that it is possible to mesure the brain functions by diffusion-weighted MRI (DW-MRI) in which visualizes diffusing water molecules in minute stractures such as neurons. This approach is based on the fact that neuronal cells in the brain swells when the neural activation occures. Its spatial and temporal resolutions are superior to those of fMRI with BOLD contrast. In the present study,with the Monte-Cairo method we simulated the motions of water molecules in the restricted stractures whose sizes were similar to those of neurons to find appropriate imaging parametrs for DW-MRI. Simulation results demonstrated that imaging parameters and the size of restricted area may change signal intensities. Furthermore, it was found that the difference of signal intensities due to the change in the size of restricted areas largely depends on the q-value which is the one of imaging parameters. These results indicate that we can estimate the imaging parameters which maximize the difference of signal intensities in DWI between before and after cell swelling by this simulation. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Diffusion Weighted Imaging / restricted diffusion / functional Magnetic Resonance Imaging |
| Paper # | IE2009-41,PRMU2009-32,MI2009-32 |
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| Conference Information | |
| Committee | IE |
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| Conference Date | 2009/5/21(1days) |
| Place (in Japanese) | (See Japanese page) |
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| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Image Engineering (IE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Simulation studies on appropriate imaging parameters for diffusion weighted function MRI |
| Sub Title (in English) | |
| Keyword(1) | Diffusion Weighted Imaging |
| Keyword(2) | restricted diffusion |
| Keyword(3) | functional Magnetic Resonance Imaging |
| 1st Author's Name | Shizue NAGAHARA |
| 1st Author's Affiliation | Graduate School of Engineering, Kyoto University() |
| 2nd Author's Name | Takenori OIDA |
| 2nd Author's Affiliation | Graduate School of Engineering, Kyoto University |
| 3rd Author's Name | Tetsuo KOBAYASI |
| 3rd Author's Affiliation | Graduate School of Engineering, Kyoto University |
| Date | 2009-05-29 |
| Paper # | IE2009-41,PRMU2009-32,MI2009-32 |
| Volume (vol) | vol.109 |
| Number (no) | 63 |
| Page | pp.pp.- |
| #Pages | 6 |
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