Presentation 2009-05-29
Development and performance evaluation of automatic segmentation method of cerebral arteries in MRA images by use of large image database
Tatsunori ASANO, Yoshikazu UCHIYAMA, Ryujiro YOKOYAMA, Takeshi HARA, Hiroshi FUJITA, Toru IWAMA, Hiroaki HOSHI,
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Abstract(in English) Computer-aided diagnosis (CAD) schemes for the detection of cerebrovascular diseases such as unruptured aneurysm and stenosis have been developed. The accurate segmentation of cerebral arteries in MRA images is an essential component of these CAD schemes. The purpose of this study is to develop a computerized method for segmenting cerebral arteries. For the segmentation of the cerebral arteries, we first used a gray level transformation to calibrate voxel values. To adjust variations in the positioning of patients, registration was subsequently employed to maximize the overlapping of the cerebral arteries in the target image and reference image. The cerebral arteries were then segmented from the background using gray level thresholding and region growing techniques. Finally, rule-based schemes with image features such as size, shape, and anatomical location were employed to distinguish between cerebral arteries and false positives. Our method was applied to 876 clinical cases. The result of subjective evaluation indicated that 98.1% of the cases achieved acceptable segmentation results. In addition, the objective evaluation which measures the overlap between the computer segmentation and manual segmentation indicated that the overlap of the randomly selected 50 cases was 0.869. Therefore, our computerized method would be useful in CAD schemes for the segmentation of the cerebral arteries in MRA images.
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Keyword(in English) Magnetic resonance angiography / Large image database / Vessel segmentation / Computer-aided diagnosis
Paper # IE2009-34,PRMU2009-25,MI2009-25
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Committee IE
Conference Date 2009/5/21(1days)
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Paper Information
Registration To Image Engineering (IE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Development and performance evaluation of automatic segmentation method of cerebral arteries in MRA images by use of large image database
Sub Title (in English)
Keyword(1) Magnetic resonance angiography
Keyword(2) Large image database
Keyword(3) Vessel segmentation
Keyword(4) Computer-aided diagnosis
1st Author's Name Tatsunori ASANO
1st Author's Affiliation Department of Intelligent Image Information, Graduate School of Medicine, Gifu University()
2nd Author's Name Yoshikazu UCHIYAMA
2nd Author's Affiliation Department of Biomedical informatics, Graduate School of Medicine, Gifu University
3rd Author's Name Ryujiro YOKOYAMA
3rd Author's Affiliation Department of Intelligent Image Information, Graduate School of Medicine, Gifu University
4th Author's Name Takeshi HARA
4th Author's Affiliation Department of Intelligent Image Information, Graduate School of Medicine, Gifu University
5th Author's Name Hiroshi FUJITA
5th Author's Affiliation Department of Intelligent Image Information, Graduate School of Medicine, Gifu University
6th Author's Name Toru IWAMA
6th Author's Affiliation Department of Neurosurgery, Graduate School of Medicine, Gifu University
7th Author's Name Hiroaki HOSHI
7th Author's Affiliation Department of Radiology, Graduate School of Medicine, Gifu University
Date 2009-05-29
Paper # IE2009-34,PRMU2009-25,MI2009-25
Volume (vol) vol.109
Number (no) 63
Page pp.pp.-
#Pages 5
Date of Issue