Presentation 2009-01-19
The significance of a nonlinear transformation and a role of local neurons in the Drosophila primary olfactory center
Ryota SATOH, Masahumi OIZUMI, Hokto KAZAMA, Masato OKADA,
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Abstract(in English) Recent investigations have shown that, in the Drosophila olfactory system, olfactory receptor neurons(ORNs) are comparatively narrowly tuned to odors while second-order projection neurons(PNs) are broadly tuned. This results from a nonlinear transformation between ORN and PN responses. Since PNs will be able to use their dynamic range more efficiently than ORNs, this transformation is considered to be helpful for the decoder to discriminate between odors. However, there are no quantitative arguments for this role. In this study, we modeled a neural circuit of the Drosophila primary olfactory center, and investigated quantitatively this role based on infomax principle.
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Keyword(in English) Drosophila / Olfactory system / McCulloch-Pitts model / mutual information
Paper # NC2008-94
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Committee NC
Conference Date 2009/1/12(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
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Title (in English) The significance of a nonlinear transformation and a role of local neurons in the Drosophila primary olfactory center
Sub Title (in English)
Keyword(1) Drosophila
Keyword(2) Olfactory system
Keyword(3) McCulloch-Pitts model
Keyword(4) mutual information
1st Author's Name Ryota SATOH
1st Author's Affiliation Graduate School of Frontier Science, The University of Tokyo()
2nd Author's Name Masahumi OIZUMI
2nd Author's Affiliation Graduate School of Frontier Science, The University of Tokyo:the Japan Society for the Promotion of Science
3rd Author's Name Hokto KAZAMA
3rd Author's Affiliation The Neurobiology Department at Harvard Medical School
4th Author's Name Masato OKADA
4th Author's Affiliation Graduate School of Frontier Science, The University of Tokyo:RIKEN Brain Science Institute
Date 2009-01-19
Paper # NC2008-94
Volume (vol) vol.108
Number (no) 383
Page pp.pp.-
#Pages 6
Date of Issue