Presentation 2009-01-24
Platinum microelectrodes for neurophysiology
Kazutoshi KOHIRA, Tamami MOTOMURA, Hidetaka YASUOKA, Yuki HAYASHIDA, Nobuki MURAYAMA,
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Abstract(in English) Recently, the prostheses for human nervous systems to treat incurable neural diseases are colleting much attention in the field of medical bioengineering. One of those is expected to compensate the disabled neural functions by means of the electrical stimulation delivered from implanted microelectrodes. In order to achieve higher spatial resolution of the stimulation, the electrodes are required to have lower electrical impedance so that the electrode tip can be as small as the single neuron size. For this purpose, however, physiological experiments should be conducted to quantitatively elucidate the neuronal response properties with the spatially localized stimuli, in the single neuron level. In this study, therefore, we have developed a new method for constructing metal microelectrodes available for in-vitro physiological experiments. We employed the glass micro-pipettes commonly used in the intracellular recordings as the casing, and inserted a metal wire into the micropipette, and then electroplated the platinum black onto the wire tip to fill the inside of micropipette. Furthermore, we examined if those platinum micro-electrodes can be used for the electrical stimulation to the biological neurons in electrophysiological experiments.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) neuronal prosthesis / electrophysiology / micro electrode / electroplating / platinum black
Paper # MBE2008-93
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Conference Information
Committee MBE
Conference Date 2009/1/16(1days)
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Paper Information
Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Platinum microelectrodes for neurophysiology
Sub Title (in English)
Keyword(1) neuronal prosthesis
Keyword(2) electrophysiology
Keyword(3) micro electrode
Keyword(4) electroplating
Keyword(5) platinum black
1st Author's Name Kazutoshi KOHIRA
1st Author's Affiliation Graduate School of Science and Technology, Kumamoto University()
2nd Author's Name Tamami MOTOMURA
2nd Author's Affiliation Graduate School of Science and Technology, Kumamoto University
3rd Author's Name Hidetaka YASUOKA
3rd Author's Affiliation Graduate School of Science and Technology, Kumamoto University
4th Author's Name Yuki HAYASHIDA
4th Author's Affiliation Graduate School of Science and Technology, Kumamoto University
5th Author's Name Nobuki MURAYAMA
5th Author's Affiliation Graduate School of Science and Technology, Kumamoto University
Date 2009-01-24
Paper # MBE2008-93
Volume (vol) vol.108
Number (no) 405
Page pp.pp.-
#Pages 4
Date of Issue