Presentation 2008-11-07
Effect of Neural Networks and Learning Data to Neuronal Activities
Masaaki TAKAHASHI, Kiyohisa NATSUME,
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Abstract(in English) In order to simulate neuronal electrical activities, we must estimate the dynamics of channel conductances from physiological experimental data. However, this approach requires the formulation of differential equations that express the time course of channel conductance. On the other hand, if the dynamics are automatically estimated neuronal activities can be easily simulated. By using a neural network (NN) which can learn and reproduce the dynamics, it is possible to estimate the dynamics of channel conductances without formulating the differential equations. We estimated the dynamics of the Na^+ and K^+ conductances of a squid giant axon using two different fully connected RNNs and were able to reproduce various neuronal activities of the axon. The reproduced activities were an action potential, a threshold, a refractory phenomenon, a rebound action potential, and periodic action potentials with a constant stimulation. Therefore, An RNN can be a useful tool to estimate the dynamics of the channel conductance of a neuron. There are several such NNs, for example, time-delayed NN, elman type NN, and fully-connected type NN. You can obtain various learning data for the NNs. The purpose is to investigate influences on neuronal activities by NNs and learning data. It was indicated that the fully-connected type NN and learning data in which voltage is changed smoothly are effective for reproducing the neuronal activities.
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Keyword(in English) Neural network / Learning data / Dynamics of channel conductance
Paper # NC2008-59
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Committee NC
Conference Date 2008/10/31(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Effect of Neural Networks and Learning Data to Neuronal Activities
Sub Title (in English)
Keyword(1) Neural network
Keyword(2) Learning data
Keyword(3) Dynamics of channel conductance
1st Author's Name Masaaki TAKAHASHI
1st Author's Affiliation Kyushu Institute of Technology()
2nd Author's Name Kiyohisa NATSUME
2nd Author's Affiliation Kyushu Institute of Technology
Date 2008-11-07
Paper # NC2008-59
Volume (vol) vol.108
Number (no) 281
Page pp.pp.-
#Pages 6
Date of Issue