Presentation 2008-03-13
Estimation error of MRI tracer concentration relating to blood vessel diameter
Hidetaka IIDA, Kazuhiro NAKAMURA, Yasushi KONDOH, Masanobu IBARAKI, Toshibumi KINOSHITA, Guoyue CHEN,
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Abstract(in English) Our previous research suggested that rat cerebral blood flow (CBF) in ischemic tissue using dynamic susceptibility contrast (DSC) method was over estimated. We proposed that the proportional constant between signal intensity and tracer concentration is different for normal and ischemic tissue. NMR signal reduction acquired by DSC method in a tissue including different vessel diameters was compared to computer simulated estimations. The signal reduction ratio in the tissue for dilating vessels was simulated on the appropriate assumption of the vessel diameter distribution. The results show that the proportional constant in the ischemic tissue increases with vessel dilation.
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Keyword(in English) MRI / Dynamic susceptibility contrast method / Ischemia model rat / CBF
Paper # MBE2007-116
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Committee MBE
Conference Date 2008/3/6(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Estimation error of MRI tracer concentration relating to blood vessel diameter
Sub Title (in English)
Keyword(1) MRI
Keyword(2) Dynamic susceptibility contrast method
Keyword(3) Ischemia model rat
Keyword(4) CBF
1st Author's Name Hidetaka IIDA
1st Author's Affiliation Akita Prefectural University()
2nd Author's Name Kazuhiro NAKAMURA
2nd Author's Affiliation Akita Researchi Institute for Brain and Blood Vessels
3rd Author's Name Yasushi KONDOH
3rd Author's Affiliation Akita Researchi Institute for Brain and Blood Vessels
4th Author's Name Masanobu IBARAKI
4th Author's Affiliation Akita Researchi Institute for Brain and Blood Vessels
5th Author's Name Toshibumi KINOSHITA
5th Author's Affiliation Akita Researchi Institute for Brain and Blood Vessels
6th Author's Name Guoyue CHEN
6th Author's Affiliation Akita Prefectural University
Date 2008-03-13
Paper # MBE2007-116
Volume (vol) vol.107
Number (no) 541
Page pp.pp.-
#Pages 4
Date of Issue