Presentation 2007-11-16
Evaluation of mutagenicity of complex magnetic fields with static and extremely low frequency components
Masateru IKEHATA, Saschiko YOSHIE, Yukihisa SUZUKI, Masao TAKI, Toshio HAYAKAWA,
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Abstract(in English) Mutagenicity of complex exposure to static magnetic field (MF) and 50Hz MF was investigated. We developed a exposure system that can expose biological samples to complex magnetic field with up to 5T static MF and up to 1mT 50Hz MF simultaneously. To investigate the mutagenicity for this complex field, bacterial mutation assay (Ames test) using Salmonella typhimurium TA98 and TA100, and also yeast mutation assay using Saccharomyces cerevisiae XD83 were performed. It was found that gene conversion/recombination frequency in S. cerevisiae XD83 was slightly increased by exposure to complex MF with 5T static and 1mT, 50Hz MF while point mutation frequency in S. cerevisiae and S. typhimurium was not affected. Possible mechanism and evaluation of mutagenicity will be discussed.
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Keyword(in English) Complex magnetic field / Biological effect / Mutation assay / Bacteria / Yeast / Safety estimation
Paper # EMCJ2007-91
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Conference Information
Committee EMCJ
Conference Date 2007/11/8(1days)
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Registration To Electromagnetic Compatibility (EMCJ)
Language JPN
Title (in Japanese) (See Japanese page)
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Title (in English) Evaluation of mutagenicity of complex magnetic fields with static and extremely low frequency components
Sub Title (in English)
Keyword(1) Complex magnetic field
Keyword(2) Biological effect
Keyword(3) Mutation assay
Keyword(4) Bacteria
Keyword(5) Yeast
Keyword(6) Safety estimation
1st Author's Name Masateru IKEHATA
1st Author's Affiliation Environmental Engineering Division, Railway Technical Research Institute()
2nd Author's Name Saschiko YOSHIE
2nd Author's Affiliation Environmental Engineering Division, Railway Technical Research Institute
3rd Author's Name Yukihisa SUZUKI
3rd Author's Affiliation Department of Electrical Engineering, Graduate School of Engineering, Tokyo Metoropolitan University
4th Author's Name Masao TAKI
4th Author's Affiliation Department of Electrical Engineering, Graduate School of Engineering, Tokyo Metoropolitan University
5th Author's Name Toshio HAYAKAWA
5th Author's Affiliation Environmental Engineering Division, Railway Technical Research Institute
Date 2007-11-16
Paper # EMCJ2007-91
Volume (vol) vol.107
Number (no) 310
Page pp.pp.-
#Pages 5
Date of Issue