Presentation 2007-09-20
Development of automated method for detection of multiple sclerosis candidate regions based on brain magnetic resonance images
Daisuke Yamamoto, Hidetaka Arimura, Shingo Kakeda, Yasuo Yamashita, Seiji Kumazawa, Fukai Toyofuku, Yoshiharu Higashida, Yukunori Korogi,
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Abstract(in English) The severity and symptom of multiple sclerosis (MS) depend on its location, shape, and area. It is very important to evaluate the temporal change of MS regions in terms of location, shape, and area for estimation of MS progression. Our aim of this study was to develop an automated method for detection of MS candidate regions based on three types of brain magnetic resonance (MR) images, i.e., T1-, T2-weighted images, and fluid attenuated inversion-recovery (FLAIR) images. The MS candidate regions were identified based on a multiple gray level thresholding technique and a region growing technique on a subtraction image between a T1-image and a FLAIR image. The candidate regions were determined by monitoring the interval changes of image feature values for region growing based on pixel value. Eight image features were determined for each candidate region, and many false positive regions were removed by using simple rules and a support vector machine (SVM). We applied our method to 24 slices of four MS cases, which included 80 MS regions. As a result, 87.5% of MS regions were detected without false positives per slice.
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Keyword(in English) computer-aided diagnosis (CAD) / multiple sclerosis (MS) / magnetic resonance imaging (MRI) / image feature analysis
Paper # MI2007-45
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Committee MI
Conference Date 2007/9/13(1days)
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Paper Information
Registration To Medical Imaging (MI)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Development of automated method for detection of multiple sclerosis candidate regions based on brain magnetic resonance images
Sub Title (in English)
Keyword(1) computer-aided diagnosis (CAD)
Keyword(2) multiple sclerosis (MS)
Keyword(3) magnetic resonance imaging (MRI)
Keyword(4) image feature analysis
1st Author's Name Daisuke Yamamoto
1st Author's Affiliation Kyushu University()
2nd Author's Name Hidetaka Arimura
2nd Author's Affiliation Kyushu University
3rd Author's Name Shingo Kakeda
3rd Author's Affiliation University of Occupational and Environmental Health
4th Author's Name Yasuo Yamashita
4th Author's Affiliation Kyushu University Hospital
5th Author's Name Seiji Kumazawa
5th Author's Affiliation Kyushu University
6th Author's Name Fukai Toyofuku
6th Author's Affiliation Kyushu University
7th Author's Name Yoshiharu Higashida
7th Author's Affiliation Kyushu University
8th Author's Name Yukunori Korogi
8th Author's Affiliation University of Occupational and Environmental Health
Date 2007-09-20
Paper # MI2007-45
Volume (vol) vol.107
Number (no) 220
Page pp.pp.-
#Pages 2
Date of Issue