Presentation 2007-03-16
Modeling and Simulation of the Sense of Agency in Schizophrenia
Mihoko OTAKE, Kohei ARAI, Takaki MAEDA, Motoichiro KATO, Toshihisa TAKAGI, Hajime ASAMA,
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Abstract(in English) Schizophrenic patients have abnormal sense of agency. The patients who sometimes attribute their own actions to the intentions of others may perceive themselves as causing events which they do not in fact control, when they feel they are hi voluntary movement. Firstly, we tested three cases of motor control and sense of agency. The first is of normal subjects. The second is of schizophrenia subjects hi voluntary movement. The third is of schizophrenia subjects in involuntary movement. The proposed model successfully described the discrepancy of attribution in schizophrenia. Secondly, the authors propose method for simulating the cognitive deficit in schizophrenia whose data are comparable to the experimental data. The output of the proposed model is mapped onto the corresponding brain area based on Talairach atlas. The simulation results of this study well describe the experimental results of a schizophrenic cerebral pattern of activation.
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Keyword(in English) neural model / schizophrenia / sense of agency / voluntary movement / attribution
Paper # NC2006-193
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Committee NC
Conference Date 2007/3/9(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Modeling and Simulation of the Sense of Agency in Schizophrenia
Sub Title (in English)
Keyword(1) neural model
Keyword(2) schizophrenia
Keyword(3) sense of agency
Keyword(4) voluntary movement
Keyword(5) attribution
1st Author's Name Mihoko OTAKE
1st Author's Affiliation Resarch into Artifacts, Center for Engineering, University of Tokyo:Science Integration Program-Humans, University of Tokyo:PRESTO JST()
2nd Author's Name Kohei ARAI
2nd Author's Affiliation Resarch into Artifacts, Center for Engineering, University of Tokyo
3rd Author's Name Takaki MAEDA
3rd Author's Affiliation School of Medicine, Keio University
4th Author's Name Motoichiro KATO
4th Author's Affiliation School of Medicine, Keio University
5th Author's Name Toshihisa TAKAGI
5th Author's Affiliation Science Integration Program-Humans, University of Tokyo
6th Author's Name Hajime ASAMA
6th Author's Affiliation Resarch into Artifacts, Center for Engineering, University of Tokyo
Date 2007-03-16
Paper # NC2006-193
Volume (vol) vol.106
Number (no) 590
Page pp.pp.-
#Pages 4
Date of Issue