| Presentation | 2006-12-05 Simulation Analysis of Transmitter Release in Response to Light in Retinal ON-type Bipolar Cells Tomokatsu KAWAKITA, Akito ISHIHARA, Masao TACHIBANA, Shiro USUI, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Retinal bipolar cells evoke graded photoresponses, which regulate the transmitter release. Here, we constructed a mathematical model of the Ca^<2+> and transmitter release coupling based on electrophysiological data that have been reported. This model could simulate the voltage and Ca^<2+> dependence of transmitter release. We also examined the relationship between the phasic and tonic components of photoresponses and the transmitter release. The phasic component of photoresponses triggered the fast component of release, whereas the tonic component caused the sustained release supported by the vesicle supply from the reservoir pool. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Retina / Bipolar Cell / Synapse / Transmitter Release / Photoresponse / Mathematical Model |
| Paper # | NC2006-71 |
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| Conference Information | |
| Committee | NC |
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| Conference Date | 2006/11/28(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Simulation Analysis of Transmitter Release in Response to Light in Retinal ON-type Bipolar Cells |
| Sub Title (in English) | |
| Keyword(1) | Retina |
| Keyword(2) | Bipolar Cell |
| Keyword(3) | Synapse |
| Keyword(4) | Transmitter Release |
| Keyword(5) | Photoresponse |
| Keyword(6) | Mathematical Model |
| 1st Author's Name | Tomokatsu KAWAKITA |
| 1st Author's Affiliation | RIKEN Brain Science Institute:Department of Psychology, Graduate School of Humanities and Sociology, The University of Tokyo() |
| 2nd Author's Name | Akito ISHIHARA |
| 2nd Author's Affiliation | School of Life System Science and Technology, Chukyo University |
| 3rd Author's Name | Masao TACHIBANA |
| 3rd Author's Affiliation | Department of Psychology, Graduate School of Humanities and Sociology, The University of Tokyo |
| 4th Author's Name | Shiro USUI |
| 4th Author's Affiliation | RIKEN Brain Science Institute |
| Date | 2006-12-05 |
| Paper # | NC2006-71 |
| Volume (vol) | vol.106 |
| Number (no) | 407 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |