Presentation 2006-10-11
Controlling synfire chain by inhibitory synaptic input
Takashi SHINOZAKI, Hidenori CATEAU, Hidetoshi URAKUBO, Masato OKADA,
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Abstract(in English) We report that the inhibitory synaptic input can control the transmission of synfire chain. Synfire chain is a phenomenon in which synchronous firings transmit between groups of neurons. Many previous studies discussed synfire chain as a fixed cable, and no studies investigated to control synfire chain flexibly. In this study, we numerically analyze the Hodgkin-Huxley model in order to examine whether the synfire chain can be controlled by topdown signals. As a result of simulation, inhibitory synaptic input 6ms before the pulse packet input with short duration strongly facilitated the transmission of synfire chain. Moreover, that 1ms after the pulse packet input strongly depressed the transmission of synfire chain. In Conclusion, synfire chain could be controlled by a inhibitory synaptic input, and could performed dynamically and functionally.
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Keyword(in English) synfire chain / Hodgkin-Huxley model / rebound firing / postinhibitory facilitation / numerical analysis
Paper # NC2006-45
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Committee NC
Conference Date 2006/10/4(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
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Title (in English) Controlling synfire chain by inhibitory synaptic input
Sub Title (in English)
Keyword(1) synfire chain
Keyword(2) Hodgkin-Huxley model
Keyword(3) rebound firing
Keyword(4) postinhibitory facilitation
Keyword(5) numerical analysis
1st Author's Name Takashi SHINOZAKI
1st Author's Affiliation RIKEN Brain Science Institute()
2nd Author's Name Hidenori CATEAU
2nd Author's Affiliation RIKEN Brain Science Institute
3rd Author's Name Hidetoshi URAKUBO
3rd Author's Affiliation Graduate School of Science, University of Tokyo
4th Author's Name Masato OKADA
4th Author's Affiliation RIKEN Brain Science Institute:Graduate School of Frontier Sciences, University of Tokyo
Date 2006-10-11
Paper # NC2006-45
Volume (vol) vol.106
Number (no) 279
Page pp.pp.-
#Pages 6
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