Presentation | 2006-06-15 Inference of ancestral RecA protein by EM algorithm Yuri NAGAI, Hitoshi KURUMIZAKA, Noboru MURATA, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | Protein RecA plays a center role to restore DNA when it is damaged because of ultraviolet rays. It is thought that the repair activity of the ancient RecA protein was stronger than that of present one, because ancient earth was exposed by a strong electromagnetic radiation. A past protein was estimated by comparing the amino acid sequences of the RecA protein exists in a present microorganism. Currently, parents arrays are estimated from the majority decision of those groups, classified by some known amino acid sequences, using MCMC method. However, the result of the simulation shows the poor accuracy. Therefore, instead of using MCMC, we use the EM method to estimate how to classify proteins. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | MCMC / Gibbs sampling / EM algorithm / RecA protein |
Paper # | NC2006-21 |
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Committee | NC |
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Conference Date | 2006/6/8(1days) |
Place (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | Neurocomputing (NC) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Inference of ancestral RecA protein by EM algorithm |
Sub Title (in English) | |
Keyword(1) | MCMC |
Keyword(2) | Gibbs sampling |
Keyword(3) | EM algorithm |
Keyword(4) | RecA protein |
1st Author's Name | Yuri NAGAI |
1st Author's Affiliation | Waseda University() |
2nd Author's Name | Hitoshi KURUMIZAKA |
2nd Author's Affiliation | Waseda University |
3rd Author's Name | Noboru MURATA |
3rd Author's Affiliation | Waseda University |
Date | 2006-06-15 |
Paper # | NC2006-21 |
Volume (vol) | vol.106 |
Number (no) | 101 |
Page | pp.pp.- |
#Pages | 6 |
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