Presentation | 2006-06-15 Building a New Mutation Model based on Bayesian Networks and estimation by a modified Belief Propagation algorithm Yoshinori DOI, Noboru MURATA, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | It is thought that ancient DNA repair proteins were more active than present ones, and obtaining the ancient DNA repair proteins would be helpful for hereditary diseases such as cancer. We propose a mutation model using Bayesian Networks and a modified the belief propagation algorithm, which is applied to estimate an ancient protein from multiple proteins that are present. Also, we applied the cross-validation to derive an optimum parameter. We virtually generated multiple proteins from an ancient protein following a specific mutation probability, and evaluated our model by estimating the ancient protein by the proposed model. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | Bayesian Networks / Bayes estimation / Belief Propagation / Mutation model |
Paper # | NC2006-20 |
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Committee | NC |
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Conference Date | 2006/6/8(1days) |
Place (in Japanese) | (See Japanese page) |
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Registration To | Neurocomputing (NC) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Building a New Mutation Model based on Bayesian Networks and estimation by a modified Belief Propagation algorithm |
Sub Title (in English) | |
Keyword(1) | Bayesian Networks |
Keyword(2) | Bayes estimation |
Keyword(3) | Belief Propagation |
Keyword(4) | Mutation model |
1st Author's Name | Yoshinori DOI |
1st Author's Affiliation | Waseda University() |
2nd Author's Name | Noboru MURATA |
2nd Author's Affiliation | Waseda University |
Date | 2006-06-15 |
Paper # | NC2006-20 |
Volume (vol) | vol.106 |
Number (no) | 101 |
Page | pp.pp.- |
#Pages | 6 |
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