| Presentation | 2006-06-15 Normalization of DNA Microarray data with BIG Model Comparison Takeo OKAZAKI, Madoka KAMIYA, Hitoshi AFUSO, Morikazu NAKAMURA, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | DNA Microarray data, which are efficient for estimation and identification of genetic network, have a large variation due to those experimental environment and measurement. Standardization by an appropriate bias correction is needed for the comparison and the data integration between two or more experiments. On grounds of normality of distribution in the ideal expression data, some adjustment methods that considers a specific bias for specific expression data has been proposed. In this research, after all combinations of assumed multiple biases and the adjustment methods were modeled, and the appropriate model by BIG was selected for normalization of expression data. The proposal method was applied to a yeast, mouse, and human microarray data from Stanford MicroArray Database, and the comparison experiment result with previous methods was shown so far. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | DNA Microarray / Gene Expression data / Normailization / BIC |
| Paper # | NC2006-17 |
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| Conference Information | |
| Committee | NC |
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| Conference Date | 2006/6/8(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Vice Chair | |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Normalization of DNA Microarray data with BIG Model Comparison |
| Sub Title (in English) | |
| Keyword(1) | DNA Microarray |
| Keyword(2) | Gene Expression data |
| Keyword(3) | Normailization |
| Keyword(4) | BIC |
| 1st Author's Name | Takeo OKAZAKI |
| 1st Author's Affiliation | Information Engineering, Fucalty of Engineering, University of the Ryukyus() |
| 2nd Author's Name | Madoka KAMIYA |
| 2nd Author's Affiliation | Information Engineering, Graduate School of Science and Engineering, University of the Ryukyus |
| 3rd Author's Name | Hitoshi AFUSO |
| 3rd Author's Affiliation | Information Engineering, Graduate School of Science and Engineering, University of the Ryukyus |
| 4th Author's Name | Morikazu NAKAMURA |
| 4th Author's Affiliation | Information Engineering, Fucalty of Engineering, University of the Ryukyus |
| Date | 2006-06-15 |
| Paper # | NC2006-17 |
| Volume (vol) | vol.106 |
| Number (no) | 101 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |